Evidence map›Paper›PMID 19541782›Full record

ArticleJournal of medical microbiology2009

Characterization of cytotoxic necrotizing factor 1-producing Escherichia coli strains from faeces of healthy macaques.

Heather R Martin, Nancy S Taylor, Ellen M Buckley, Robert P Marini, Mary M Patterson, James G Fox

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Multidrug resistance in pathogenicFrontiers in veterinary science · 2024
    Article
  2. Review
  3. Article
  4. GenotoxicComparative medicine · 2019
    Article
  5. CytotoxicGut pathogens · 2017
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Heather R MartinDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Nancy S TaylorDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Ellen M BuckleyDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Robert P MariniDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Mary M PattersonDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
James G FoxDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.

Funding

TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LEVINE, STUART S · 1985 to 2020
$25.6M
POSTDOCTORAL TRAINING IN COMPARATIVE MEDICINET32RR007036 · NCRR · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI FOX, JAMES G · 1988 to 2011
$3.6M
NCRR NIH HHS T32 RR007036NCRR NIH HHS T32 RR07036NIEHS NIH HHS P30 ES002109NIEHS NIH HHS P30 ES02109
6 · The paper itself

Abstract

Twenty-five (27 %) of 92 clinically normal macaques were found to have beta-haemolytic Escherichia coli isolated from their faeces. Five of six isolates chosen for further characterization had multiple antibiotic resistance and were PCR-positive for cytotoxic necrotizing factor 1 (cnf1) with a demonstrated cytopathic effect in vitro. By repetitive element sequence-based PCR genotyping, genetic similarity was established for selected isolates. We believe this to be the first report of E. coli strains producing CNF1 in non-human primates.

Indexed as

AnimalsBacterial ToxinsDNA, BacterialDNA FingerprintingEscherichia coliEscherichia coli ProteinsFecesGenes, BacterialHeLa CellsHumansMacaca fascicularisMacaca mulattaSerotypingVirulenceBacterial Toxinscytotoxic necrotizing factor type 1DNA, BacterialEscherichia coli Proteins

Identifiers

PMID19541782
PMCPMC2743768

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.