ArticleThe European respiratory journal2009
Pesticide use and adult-onset asthma among male farmers in the Agricultural Health Study.
Article in The European respiratory journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 162 citations in OpenAlex.
- Respiratory and Allergic Effects in Children Exposed to Pesticides-A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Is pesticide exposure a cause of obstructive airways disease?European respiratory review : an official journal of the European Respiratory Society · 2014Pooled it
- Article
- Reliable LC-MS/MS method integrated with a linear retention index approach for multiresidue pesticide analysis in hemp seed oil.Analytical and bioanalytical chemistry · 2026Article
- Exposure to Air Pollution and the Prevalence of Respiratory Symptoms in Northeast Ohio Farmworkers.Journal of immigrant and minority health · 2025Article
- Article
- A systematic review of pesticide exposure, associated risks, and long-term human health impacts.Toxicology reports · 2024Review
- Associations of environmental chemical exposures measured in personal silicone wristbands with sociodemographic factors, COVID-19 restrictions, and child respiratory health.Environmental research · 2024Article
- Article
- Prevalence and concentration of pesticides in European waters: A protocol for systematic review and meta-analysis.PloS one · 2024Article
- Impacts of Agricultural Pesticide Contamination: An Integrated Risk Assessment of Rural Communities of Eswatini.Toxics · 2023Article
- Review
- Adhesion Molecules in Lung Inflammation from Repeated Glyphosate Exposures.International journal of environmental research and public health · 2023Article
- Formulation of biofungicides based on Streptomyces caeruleatus strain ZL-2 spores and efficacy against Rhizoctonia solani damping-off of tomato seedlings.Archives of microbiology · 2022Article
- Associations between airborne crude oil chemicals and symptom-based asthma.Environment international · 2022Article
- Respiratory and allergic health effects in children living near agriculture: A review.The Science of the total environment · 2022Review
- Article
- Insecticide Exposure and Risk of Asthmatic Symptoms: A Systematic Review and Meta-Analysis.Toxics · 2021Review
- CD34+ derived macrophage and dendritic cells display differential responses to paraquat.Toxicology in vitro : an international journal published in association with BIBRA · 2021Article
- Immunotoxic role of organophosphates: An unseen risk escalating SARS-CoV-2 pathogenicity.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2021Review
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
Although specific pesticides have been associated with wheeze in farmers, little is known about pesticides and asthma. Data from 19,704 male farmers in the Agricultural Health Study were used to evaluate lifetime use of 48 pesticides and prevalent adult-onset asthma, defined as doctor-diagnosed asthma after the age of 20 yrs. Asthma cases were categorised as allergic (n = 127) and nonallergic (n = 314) based on their history of eczema or hay fever. Polytomous logistic regression, controlling for age, state, smoking and body mass, was used to assess pesticide associations. High pesticide exposure events were associated with a doubling of both allergic and nonallergic asthma. For ever-use, 12 individual pesticides were associated with allergic asthma and four with nonallergic asthma. For allergic asthma, coumaphos (OR 2.34; 95% CI 1.49-3.70), heptachlor (OR 2.01; 95% CI 1.30-3.11), parathion (OR 2.05; 95% CI 1.21-3.46), 80/20 mix (carbon tetrachloride/carbon disulfide) (OR 2.15; 95% CI 1.23-3.76) and ethylene dibromide (OR 2.07; 95% CI 1.02-4.20) all showed ORs of >2.0 and significant exposure-response trends. For nonallergic asthma, DDT (dichlorodiphenyltrichloroethane) showed the strongest association (OR 1.41; 95% CI 1.09-1.84), but with little evidence of increasing asthma with increasing use. Current animal handling and farm activities did not confound these results. There was little evidence that allergy alone was driving these associations. In conclusion, pesticides may be an overlooked contributor to asthma risk among farmers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.