ReviewCurrent opinion in immunology2009
The evolved functions of CD1 during infection.
Review in Current opinion in immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 45 citations in OpenAlex.
- Nonclassical MHC-I Molecules: Emerging Therapeutic Targets in Next-Generation Immunotherapy.MedComm · 2026Review
- Clinical assessment and transcriptome analysis of host immune responses in a vaccination-challenge study using a glycoprotein G deletion mutant vaccine strain of infectious laryngotracheitis virus.Frontiers in immunology · 2024Article
- CD1 and iNKT cells mediate immune responses against the GBS hemolytic lipid toxin induced by a non-toxic analog.PLoS pathogens · 2023Article
- Development and function of chicken XCR1Frontiers in immunology · 2023Article
- Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors.Nature communications · 2022Article
- Conservation of molecular and cellular phenotypes of invariant NKT cells between humans and non-human primates.Immunogenetics · 2019Article
- Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling.Cell research · 2019Article
- Harnessing Invariant NKT Cells to Improve Influenza Vaccines: A Pig Perspective.International journal of molecular sciences · 2017Review
- Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection.Tuberculosis (Edinburgh, Scotland) · 2017Article
- T cell receptor recognition of CD1b presenting a mycobacterial glycolipid.Nature communications · 2016Article
- Carbohydrates as T-cell antigens with implications in health and disease.Glycobiology · 2016Review
- Donor-unrestricted T cells in the human CD1 system.Immunogenetics · 2016Review
- Molecular Analysis of Lipid-Reactive Vδ1 γδ T Cells Identified by CD1c Tetramers.Journal of immunology (Baltimore, Md. : 1950) · 2016Article
- Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase.Science translational medicine · 2016Article
- Function and expression of CD1d and invariant natural killer T-cell receptor in the cotton rat (Sigmodon hispidus).Immunology · 2015Article
- The burgeoning family of unconventional T cells.Nature immunology · 2015Review
- Lipid and small-molecule display by CD1 and MR1.Nature reviews. Immunology · 2015Review
- Bee venom processes human skin lipids for presentation by CD1a.The Journal of experimental medicine · 2015Article
- Article
- Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by αβ T cells.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
CD1 proteins display lipid antigens to T cell receptors. Studies using CD1d tetramers and CD1d-deficient mice provide important insight into the immunological functions of invariant NK T cells (iNKT) during viral and bacterial infections. However, the mouse CD1 locus is atypical because it encodes only CD1d, whereas most mammalian species have retained many CD1 genes. Viewed from the perspective that CD1 is a diverse gene family that activates several of classes of T cells, new insights into lipid loading and infection response are emerging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.