Evidence map›Paper›PMID 19541426›Full record

ReviewPsychoneuroendocrinology2009

Modulation of steroid action in the central and peripheral nervous systems by nuclear receptor coactivators.

Marc J Tetel

Abstract readReview
In one paragraph

Review in Psychoneuroendocrinology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Marc J TetelNeuroscience Program, Wellesley College, 106 Central St., Wellesley, MA 02481, USA. mtetel@wellesley.edu
Wellesley College · US

Funding

Mechanisms of Steroid Hormone Action in BrainR01DK061935 · NIDDK · WELLESLEY COLLEGE · PI TETEL, MARC JEFFREY · 2002 to 2014
$2.7M
NIDDK NIH HHS R01 DK061935NIDDK NIH HHS R01DK61935
6 · The paper itself

Abstract

Steroid hormones act in the central and peripheral nervous systems to regulate a variety of functions, including development, cell proliferation, cognition and behavior. Many of these effects of steroid hormones are mediated by their respective receptors, which are members of the nuclear receptor superfamily of transcriptional activators. A variety of cell culture studies reveal that nuclear receptor coactivators are recruited to the steroid receptor complex and are critical in modulating steroid-dependent transcription. Thus, in addition to the availability of the hormone and its receptor, the expression of nuclear receptor coactivators is essential for modulating steroid receptor-mediated transcription. This review will discuss the significance of nuclear receptor coactivators in modulating steroid-dependent gene expression in the central and peripheral nervous systems and the regulation of behavior.

Indexed as

AnimalsBrainCentral Nervous SystemGene Expression RegulationModels, BiologicalNeurotransmitter AgentsNuclear Receptor CoactivatorsPeripheral Nervous SystemReceptors, SteroidSexual Behavior, AnimalNeurotransmitter AgentsNuclear Receptor CoactivatorsReceptors, Steroid

Identifiers

PMID19541426
PMCPMC2795054
OpenAlexW2164657802

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.