Evidence map›Paper›PMID 19540357›Full record

ReviewBiochimica et biophysica acta2009

Phospholipase D in endocytosis and endosomal recycling pathways.

Julie G Donaldson

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
  2. Protective mechanisms against Alzheimer's disease in APOE3-Christchurch homozygous astrocytes.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
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  9. Review
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  12. Frontiers in neuroscience · 2019
    Article
  13. Mechanism of membrane fusion: protein-protein interaction and beyond.International journal of physiology, pathophysiology and pharmacology · 2019
    Review
  14. Review
  15. Shot-Gun Proteomic Analysis on Roots of ArabidopsisInternational journal of molecular sciences · 2018
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Julie G DonaldsonLaboratory of Cell Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 50, Room 2503, Bethesda, MD 20892, USA. jdonalds@helix.nih.gov
National Institutes of Health · US

Funding

CELLULAR FUNCTION OF THE ADP-RIBOSYLATION FACTOR 6 GTP BINDING PROTEINZ01HL000517 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI DONALDSON, JULIE G · 1996 to 2008
$3.2M
Arf GTP-binding proteins and membrane trafficZIAHL000517 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI DONALDSON, JULIE G · 2009 to 2016
$2.6M
Intramural NIH HHS Z01 HL000517
6 · The paper itself

Abstract

The discovery that Arf GTPases, mediators of membrane traffic, activate phospholipase D (PLD) raised the possibility that Arfs could facilitate membrane traffic by altering membrane lipid composition. PLD hydrolyzes phosphatidylcholine to generate phosphatidic acid (PA), a lipid that favors membranes with negative curvature and thus can facilitate both membrane fission and fusion. This review examines studies that have reported a role for PLD in endocytosis and membrane recycling from endocytic pathways.

Indexed as

EndocytosisSignal TransductionAnimalsCell MembraneEndosomesHumansPhospholipase DReceptors, Cell SurfacePhospholipase DReceptors, Cell Surface

Identifiers

PMID19540357
PMCPMC2731818
OpenAlexW2048825955

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.