ReviewCardiovascular & hematological agents in medicinal chemistry2009
Female sexual dysfunction: therapeutic options and experimental challenges.
Review in Cardiovascular & hematological agents in medicinal chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Sexual health interventions for treating sexual dysfunction in women with female genital mutilation: A systematic review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Pooled it
- The impact of cell-based therapy on female sexual dysfunction: a systematic review and meta-analysis.Sexual medicine reviews · 2023Pooled it
- Interventions for sexual dysfunction following treatments for cancer in women.The Cochrane database of systematic reviews · 2016Pooled it
- Current and future pharmacotherapy for female sexual dysfunction.Nature reviews. Urology · 2026Review
- Female Sexual Dysfunction and Associated Factors Among Married Women in Bahir Dar, Northwest Ethiopia: A Cross-Sectional Study.Health science reports · 2025Article
- Sexual Function After Vaginal Delivery in Primiparous Women: A Perspective in the First Months Postpartum.Healthcare (Basel, Switzerland) · 2025Article
- Addressing Sexual Dysfunction in Women With Type 1 Diabetes.Clinical diabetes : a publication of the American Diabetes Association · 2025Review
- Non-Pharmacological Treatment of Autonomic Dysfunction in Parkinson's Disease and Other Synucleinopathies.Journal of Parkinson's disease · 2024Review
- Psychometric properties of the Romanian version of the female sexual function index (FSFI-RO).BMC women's health · 2023Article
- Genital Self-Image, Sexual Function, and Quality of Life Among Individuals with Vulvar and Non-Vulvar Inflammatory Dermatoses.Archives of sexual behavior · 2022Article
- Article
- Factors Associated with Postpartum Sexual Dysfunction in Spanish Women: A Cross-Sectional Study.Journal of personalized medicine · 2022Article
- Behavioral Therapies for Treating Female Sexual Dysfunctions: A State-of-the-Art Review.Journal of clinical medicine · 2022Review
- "Adipose-derived mesenchymal stem cell therapy for the management of female sexual dysfunction: Literature reviews and study design of a clinical trial".Frontiers in cell and developmental biology · 2022Review
- Current Perspectives on the Beneficial Effects of Soybean Isoflavones and Their Metabolites for Humans.Antioxidants (Basel, Switzerland) · 2021Review
- Hydrogen Gas: A Novel Type of Antioxidant in Modulating Sexual Organs Homeostasis.Oxidative medicine and cellular longevity · 2021Review
- Through the Looking-Glass: Reevaluating DHEA Metabolism Through HSD3B1 Genetics.Trends in endocrinology and metabolism: TEM · 2020Review
- Gold Thread Implantation for Female Sexual Dysfunction and Vaginal Laxity: A Preliminary Investigation.Journal of menopausal medicine · 2020Article
- Evaluating co-occurrence of depression and sexual dysfunction and related factors among Iranian rural women: A population-based study.BioMedicine · 2020Article
- The rodent vaginal microbiome across the estrous cycle and the effect of genital nerve electrical stimulation.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Female sexual dysfunction (FSD) is a prevalent problem, afflicting approximately 40% of women and there are few treatment options. FSD is more typical as women age and is a progressive and widespread condition. Common symptoms associated with FSD include diminished vaginal lubrication, pain and discomfort upon intercourse, decreased sense of arousal and difficulty in achieving orgasm. Only a small percentage of women seek medical attention. In comparison to the overwhelming research and treatment for erectile dysfunction in males, specifically with the development of phosphodiesterase type 5 inhibitors, significantly less has been explored regarding FSD and treatment is primarily limited to psychological therapy. Several cardiovascular diseases have been linked with FSD including atherosclerosis, peripheral arterial disease and hypertension, all of which are also pathological conditions associated with aging and erectile dysfunction in men. Using animal models, we have expanded our understanding of FSD, however a tremendous amount is still to be learned in order to properly treat women suffering from FSD. The aim of this review is to provide the most current knowledge on FSD, advances in basic science addressing this dysfunction, and explore developing therapeutic options.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.