ArticlePloS one2009
Actin turnover is required for myosin-dependent mitochondrial movements in Arabidopsis root hairs.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Mitochondrial dynamics resolve physical-social tensions and challenges through adaptable multi-objective optimisation.bioRxiv : the preprint server for biology · 2026Article
- Selective degradation processes in plants are not limited to autophagy.Plant cell reports · 2026Review
- MDP25-VDAC3 Complex Orchestrates Actin Remodeling and Mitochondrial Dynamics to Modulate Innate Immunity in Arabidopsis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cytoskeleton as a generator of characteristic physical properties of plant cells: 'cell wall,' 'large vacuole,' and 'cytoplasmic streaming'.Biophysics and physicobiology · 2025Article
- Sugar import mediated by sugar transporters and cell wall invertases for seed development inHorticulture research · 2024Article
- Visualizing the dynamics of plant energy organelles.Biochemical Society transactions · 2023Article
- Spatiotemporal distribution of reactive oxygen species production, delivery, and use in Arabidopsis root hairs.Plant physiology · 2023Article
- Article
- Developmentally regulated mitochondrial biogenesis and cell death competence in maize pollen.BMC plant biology · 2022Article
- Novel Insights into Floral Thermogenesis: In Vivo Analyses of Mitochondrial Dynamics inInternational journal of molecular sciences · 2022Article
- Altered collective mitochondrial dynamics in the Arabidopsis msh1 mutant compromising organelle DNA maintenance.Journal of experimental botany · 2022Article
- Effects of mitochondria-selective fluorescent probes on mitochondrial movement inPlant biotechnology (Tokyo, Japan) · 2021Article
- Network analysis of Arabidopsis mitochondrial dynamics reveals a resolved tradeoff between physical distribution and social connectivity.Cell systems · 2021Article
- Mitochondrial movement during its association with chloroplasts in Arabidopsis thaliana.Communications biology · 2021Article
- Mitochondrial dynamics and segregation during the asymmetric division ofQuantitative plant biology · 2020Article
- Arabidopsis myosin XI: a motor rules the tracks.Plant physiology · 2014Article
- ER network dynamics are differentially controlled by myosins XI-K, XI-C, XI-E, XI-I, XI-1, and XI-2.Frontiers in plant science · 2014Article
- The actin-related Protein2/3 complex regulates mitochondrial-associated calcium signaling during salt stress in Arabidopsis.The Plant cell · 2013Article
- Identification of myosin XI receptors in Arabidopsis defines a distinct class of transport vesicles.The Plant cell · 2013Article
- Structural and biomechanical basis of mitochondrial movement in eukaryotic cells.International journal of nanomedicine · 2013Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have shown that plant mitochondrial movements are myosin-based along actin filaments, which undergo continuous turnover by the exchange of actin subunits from existing filaments. Although earlier studies revealed that actin filament dynamics are essential for many functions of the actin cytoskeleton, there are little data connecting actin dynamics and mitochondrial movements. METHODOLOGY/PRINCIPAL
findingsWe addressed the role of actin filament dynamics in the control of mitochondrial movements by treating cells with various pharmaceuticals that affect actin filament assembly and disassembly. Confocal microscopy of Arabidopsis thaliana root hairs expressing GFP-FABD2 as an actin filament reporter showed that mitochondrial distribution was in agreement with the arrangement of actin filaments in root hairs at different developmental stages. Analyses of mitochondrial trajectories and instantaneous velocities immediately following pharmacological perturbation of the cytoskeleton using variable-angle evanescent wave microscopy and/or spinning disk confocal microscopy revealed that mitochondrial velocities were regulated by myosin activity and actin filament dynamics. Furthermore, simultaneous visualization of mitochondria and actin filaments suggested that mitochondrial positioning might involve depolymerization of actin filaments on the surface of mitochondria. CONCLUSIONS/SIGNIFICANCE: Base on these results we propose a mechanism for the regulation of mitochondrial speed of movements, positioning, and direction of movements that combines the coordinated activity of myosin and the rate of actin turnover, together with microtubule dynamics, which directs the positioning of actin polymerization events.
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