Evidence map›Paper›PMID 19535519›Full record

ArticleJournal of clinical microbiology2009

Detection and quantification of hepatitis C virus (HCV) by MultiCode-RTx real-time PCR targeting the HCV 3' untranslated region.

Elizabeth K Mulligan, J J Germer, Max Q Arens, Krista L D'Amore, Adrian Di Bisceglie, Nathan A Ledeboer, Michael J Moser, Andrew C Newman, Andy K O'Guin, Paul D Olivo and 5 more

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Elizabeth K MulliganEraGen Biosciences, Inc., Madison, WI 53717, USA.
J J Germer
Max Q Arens
Krista L D'Amore
Adrian Di Bisceglie
Nathan A Ledeboer
Michael J Moser
Andrew C Newman
Andy K O'Guin
Paul D Olivo
Diane S Podzorski
Kimberly A Vaughan
Joseph D Yao
Slava A Elagin
Scott C Johnson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A prototype, real-time reverse-transcription PCR assay, based on MultiCode-RTx technology, quantifying hepatitis C virus (HCV) RNA by targeting the HCV 3' untranslated region demonstrated linearity over 7 logs, with a good correlation between the quantitative results of this assay and the results of two commercially available comparator assays for 466 clinical specimens comprising all six HCV genotypes.

Indexed as

3' Untranslated RegionsHepacivirusHepatitis CHumansPlasmaReverse Transcriptase Polymerase Chain ReactionRNA, ViralSensitivity and SpecificitySerumViral Load3' Untranslated RegionsRNA, Viral

Identifiers

PMID19535519
PMCPMC2725663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.