Evidence map›Paper›PMID 19534534›Full record

ReviewJournal of medicinal chemistry2009

Recent advances in the development of polyamine analogues as antitumor agents.

Robert A Casero, Patrick M Woster

Abstract readReview
In one paragraph

Review in Journal of medicinal chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Polyamine-Drug Conjugates: Do They Boost Drug Activity?Molecules (Basel, Switzerland) · 2023
    Review
  9. Biomolecules · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Robert A CaseroSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland 21231, USA.
Patrick M Woster

Funding

Identification of LSD1 inhibitors targeting epigenetic regulation in tumor cellsR01CA149095 · NCI · WAYNE STATE UNIVERSITY · PI WOSTER, PATRICK M · 2010 to 2014
$1.3M
ANTINEOPLASTIC POLYAMINE ANALOGUESR01CA085509 · NCI · WAYNE STATE UNIVERSITY · PI WOSTER, PATRICK M · 2000 to 2004
$1.2M
NCI NIH HHS R01 CA085509NCI NIH HHS R01 CA149095NCI NIH HHS R01 CA85509
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug DiscoveryAnimalsAntineoplastic AgentsBiogenic PolyaminesBreast NeoplasmsDNAEflornithineEnzyme InhibitorsHistone Deacetylase InhibitorsHistone DemethylasesHomeostasisHumansOxidoreductases, N-DemethylatingPolyaminesStructure-Activity RelationshipAntineoplastic AgentsBiogenic PolyaminesDNAEflornithineEnzyme InhibitorsHistone Deacetylase InhibitorsHistone DemethylasesKDM1A protein, humanOxidoreductases, N-DemethylatingPolyamines

Identifiers

PMID19534534
PMCPMC2762202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.