ArticleSleep & breathing = Schlaf & Atmung2009
Diurnal variability of C-reactive protein in obstructive sleep apnea.
Article in Sleep & breathing = Schlaf & Atmung, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Trial
- Timing Matters: An Observational Study on Circadian Effects of Spinal Anesthesia in Cesarean Delivery.Life (Basel, Switzerland) · 2025Article
- Sympathetic overactivity and nocturnal diuresis in obstructive sleep apnea alter the response to hypertension therapy.Clinical hypertension · 2024Article
- Social Media Use and Its Concurrent and Subsequent Relation to a Biological Marker of Inflammation: Short-Term Longitudinal Study.Journal of medical Internet research · 2023Article
- Glycoprotein acetyls and depression: Testing for directionality and potential causality using longitudinal data and Mendelian randomization analyses.Journal of affective disorders · 2023Article
- Can inflammation predict social media use? Linking a biological marker of systemic inflammation with social media use among college students and middle-aged adults.Brain, behavior, and immunity · 2023Article
- Prospect of thioredoxin as a possibly effective tool to combat OSAHS.Sleep & breathing = Schlaf & Atmung · 2023Review
- Lack of Evidence for a Relationship Between Salivary CRP and Women's Sexual Desire: An Investigation Across Clinical and Healthy Samples.The journal of sexual medicine · 2022Article
- Comparison of C-Reactive Protein in Dried Blood Spots and Saliva of Healthy Adolescents.Frontiers in immunology · 2021Article
- Central sleep apnea and atrial fibrillation: A review on pathophysiological mechanisms and therapeutic implications.International journal of cardiology. Heart & vasculature · 2020Review
- Pronounced Diurnal Pattern of Salivary C-Reactive Protein (CRP) With Modest Associations to Circulating CRP Levels.Frontiers in immunology · 2020Article
- Monocytic C-C chemokine receptor 5 expression increases in in vitro intermittent hypoxia condition and in severe obstructive sleep apnea patients.Sleep & breathing = Schlaf & Atmung · 2019Article
- Elevated Serum Markers of Acute Kidney Injury in Patients With Obstructive Sleep Apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- The role inflammatory response genes in obstructive sleep apnea syndrome: a review.Sleep & breathing = Schlaf & Atmung · 2016Review
- What can blood biomarkers tell us about cardiovascular risk in obstructive sleep apnea?Sleep & breathing = Schlaf & Atmung · 2015Review
- Morning pentraxin3 levels reflect obstructive sleep apnea-related acute inflammation.Journal of applied physiology (Bethesda, Md. : 1985) · 2014Article
- Endothelial injury markers before and after nasal continuous positive airway pressure treatment for obstructive sleep apnoea hypopnoea syndrome.Sleep & breathing = Schlaf & Atmung · 2014Article
- Increased systemic inflammation overnight correlates with insulin resistance among children evaluated for obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2012Article
- Macrophage migratory inhibitory factor (MIF) may be a key factor in inflammation in obstructive sleep apnea.Sleep · 2011Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveThe objective of this study is to examine the diurnal variability of C-reactive protein (CRP) in obstructive sleep apnea (OSA). METHODS AND MEASUREMENTS: Participants included 44 women and men with untreated OSA (mean apnea/hypopnea index = 37.5, SD +/- 28) and 23 healthy adults with no OSA. Sleep was monitored with polysomnography in the University of California San Diego General Clinical Research Center. Over a 24-h period, blood was collected every 2 h, and CRP levels were determined.
resultsAdjusting for age, gender, and body mass index, a significant group by time interaction showed that patients with OSA had higher CRP levels during the daytime (8:00 a.m.-8:00 p.m.) versus the nighttime (10:00 p.m. until 6:00 p.m.; p < 0.001). Non-apneics showed no significant change in CRP levels during the 24 h.
conclusionsThe findings indicate that sleep apnea patients have disproportionately elevated CRP levels in the day versus the nighttime, possibly as a result of carryover effects of nighttime arousal into the daytime.
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Registered trials
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