ArticleInternational journal of legal medicine2010
MtDNA control region sequence polymorphisms and phylogenetic analysis of Malay population living in or around Kuala Lumpur in Malaysia.
Article in International journal of legal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 27 citations in OpenAlex.
- Article
- Autosomal STR Profiling and Databanking in Malaysia: Current Status and Future Prospects.Genes · 2020Article
- A genetic chronology for the Indian Subcontinent points to heavily sex-biased dispersals.BMC evolutionary biology · 2017Article
- Carriers of human mitochondrial DNA macrohaplogroup M colonized India from southeastern Asia.BMC evolutionary biology · 2016Article
- Multiplex APLP System for High-Resolution Haplogrouping of Extremely Degraded East-Asian Mitochondrial DNAs.PloS one · 2016Article
- Article
- Sequence polymorphisms of mtDNA HV1, HV2, and HV3 regions in the Malay population of Peninsular Malaysia.International journal of legal medicine · 2010Article
- Mitochondrial DNA diversity in a population from Santa Catarina (Brazil): predominance of the European input.International journal of legal medicine · 2010Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
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Abstract
Control region polymorphisms in the mitochondrial DNA of 124 unrelated individuals from the Malay population living in or around Kuala Lumpur in Malaysia were investigated and phylogenetic haplogroup lineages were determined. The intergenic COII/tRNALys 9-bp deletion, 3010 and 5178 mutations, and several coding region polymorphisms were examined to discriminate some phylogenetic haplogroups. Sequence comparison of the control regions led to the identification of 117 mitochondrial haplotypes, in which 103 types were observed in only one individual and the other nine types were shared by more than two individuals. Gene diversity was estimated to be 0.997. Phylogenetic haplogroup determination revealed that the gene pool of the modern Malay population in Malaysia consisted mainly of southeast Asian, east Asian, unidentified and unique, and aboriginal southeast-specific haplogroups. These results suggest a multi-original nature for the modern Malay population. The present database may help not only in personal identification but also in determining geographic origin in forensic casework in Malaysian, Southeast Asian and East Asian populations.
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