ArticleIntensive care medicine2009
Feasibility of non-invasive pressure support ventilation in infants with respiratory failure after extubation: a pilot study.
Article in Intensive care medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Continuous negative extrathoracic pressure or continuous positive airway pressure compared to conventional ventilation for acute hypoxaemic respiratory failure in children.The Cochrane database of systematic reviews · 2013Pooled it
- Postextubation Noninvasive Respiratory Support in Children.Respiratory care · 2025Review
- Article
- Noninvasive positive pressure ventilation in critically ill children with cardiac disease.Pediatric cardiology · 2014Observational
- Noninvasive positive pressure ventilation for acute respiratory failure in children: a concise review.Annals of intensive care · 2011Article
- Non-invasive ventilation with balloon dilatation of severe subglottic stenosis in a 10-month infant.Intensive care medicine · 2011Article
- Non invasive ventilation after extubation in paediatric patients: a preliminary study.BMC pediatrics · 2010Article
- Year in review in Intensive Care Medicine 2009. Part III: mechanical ventilation, acute lung injury and respiratory distress syndrome, pediatrics, ethics, and miscellanea.Intensive care medicine · 2010Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the feasibility and effects of non-invasive pressure support ventilation (NIV) on the breathing pattern in infants developing respiratory failure after extubation.
designProspective pilot clinical study; each patient served as their own control.
settingA nine-bed paediatric intensive care unit of a tertiary university hospital. PATIENTS: Six patients (median age 5 months, range 0.5-7 months; median weight 4.2 kg, range 3.8-5.1 kg) who developed respiratory failure after extubation.
interventionsAfter a period of spontaneous breathing (SB), children who developed respiratory failure were treated with NIV. MEASUREMENTS AND
resultsMeasurements included clinical dyspnoea score (DS), blood gases and oesophageal pressure recordings, which were analysed for respiratory rate (RR), oesophageal inspiratory pressure swing (dPes) and oesophageal pressure-time product (PTPes). All data were collected during both periods (SB and NIV). When comparing NIV with SB, DS was reduced by 44% (P < 0.001), RR by 32% (P < 0.001), dPes by 45% (P < 0.01) and PTPes by 57% (P < 0.001). A non-significant trend for decrease in PaCO(2) was observed.
conclusionIn these infants, non-invasive pressure support ventilation with turbine flow generator induced a reduction of breathing frequency, dPes and PTPes, indicating reduced load of the inspiratory muscles. NIV can be used with some benefits in infants with respiratory failure after extubation.
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