Evidence map›Paper›PMID 19532498›Full record

ArticleOptics express2007

Metal-enhanced fluorescence of an organic fluorophore using gold particles.

Jian Zhang, Joseph R Lakowicz

Abstract read
In one paragraph

Article in Optics express, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Fluorescence Spectroscopy with Metal-Dielectric Waveguides.The journal of physical chemistry. C, Nanomaterials and interfaces · 2015
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Feasibility of Using Bimetallic Plasmonic Nanostructures to Enhance the Intrinsic Emission of Biomolecules.The journal of physical chemistry. C, Nanomaterials and interfaces · 2011
    Article
  15. Article
  16. Enhanced Single-Molecule Detection using Porous Silver Membrane.The journal of physical chemistry. C, Nanomaterials and interfaces · 2010
    Article
  17. Article
  18. Plasmon-controlled fluorescence towards high-sensitivity optical sensing.Advances in biochemical engineering/biotechnology · 2009
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jian Zhang
Joseph R Lakowicz

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI BASKAKOV, ILIA V · 1993 to 2006
$7.4M
Metallic Surfaces and Particles in DNA AnalysisR01HG002655 · NHGRI · UNIVERSITY OF MARYLAND BALTIMORE · PI LAKOWICZ, JOSEPH R. · 2003 to 2012
$2.8M
Metal-Enhanced Fluorescence SensingR01EB000682 · NIBIB · UNIVERSITY OF MARYLAND BALTIMORE · PI LAKOWICZ, JOSEPH R. · 2002 to 2006
$1.7M
NCRR NIH HHS P41 RR008119NHGRI NIH HHS R01 HG002655NIBIB NIH HHS R01 EB000682
6 · The paper itself

Abstract

Particulate gold films were deposited on glass substrates by vapor deposition. Rabbit immunoglobulin G (IgG) was immobilized by physiosorption and then Alexa Fluor anti Rabbit IgG was bound to the protein-coated surfaces. Fluorescence was enhanced with increasing the Au thickness and reached saturation at 30 nm when Alexa Fluor555 anti IgG was used. We also examined the effect of silica spacers between the gold film and the labeled protein. The maximum enhancement was dependent on the thickness of silica and reach maximum at 10 nm. The maximum increase in intensity was about 6-fold. We also bound Alexa Fluor-680 anti IgG to the protein-coated surface, and the maximum enhancement was about 10-fold.

Identifiers

PMID19532498
PMCPMC2739992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.