ArticleJournal of anatomy2009
The pattern of endocranial ontogenetic shape changes in humans.
Article in Journal of anatomy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed.
- When Virchow's law fails: Crouzon syndrome as a test case for quantitative suture closure-endocranial shape relationships.Journal of anatomy · 2026Article
- Sexual dimorphism of cranial fossae in forensic anthropology: A systematic review.Journal of Taibah University Medical Sciences · 2026Review
- New Insights Into Cranial Base Ontogeny in Modern Humans Through Morphometric Analysis.American journal of biological anthropology · 2026Article
- Postnatal interaction of size and shape in the human endocranium and brain structures.Journal of anatomy · 2026Article
- Computational simulation of cranial soft tissue expansion on the cranium during early postnatal growth in humans.Journal of anatomy · 2026Article
- Growth and development of the precuneus in humans from birth to early adulthood.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- An inclusive anatomical network analysis of human craniocerebral topology.Journal of anatomy · 2024Article
- Quantitative morphological analysis framework of infant cranial sutures and fontanelles based on CT images.Journal of anatomy · 2024Article
- Brain structure and function: a multidisciplinary pipeline to study hominoid brain evolution.Frontiers in integrative neuroscience · 2023Article
- A comparison of intracranial volume estimation methods and their cross-sectional and longitudinal associations with age.Human brain mapping · 2022Article
- Individual variability in the nonlinear development of the corpus callosum during infancy and toddlerhood: a longitudinal MRI analysis.Brain structure & function · 2022Article
- Craniofacial orientation and parietal bone morphology in adult modern humans.Journal of anatomy · 2022Article
- Shaping modern human skull through epigenetic, transcriptional and post-transcriptional regulation of the RUNX2 master bone gene.Scientific reports · 2021Article
- Evolutionary development of the Homo antecessor scapulae (Gran Dolina site, Atapuerca) suggests a modern-like development for Lower Pleistocene Homo.Scientific reports · 2021Article
- Drimolen cranium DNH 155 documents microevolution in an early hominin species.Nature ecology & evolution · 2021Article
- A 3D basicranial shape-based assessment of local and continental northwest European ancestry among 5th to 9th century CE Anglo-Saxons.PloS one · 2021Article
- The composition of the founding population of Iceland: A new perspective from 3D analyses of basicranial shape.PloS one · 2021Article
- Late subadult ontogeny and adult aging of the human thorax reveals divergent growth trajectories between sexes.Scientific reports · 2020Article
- Modeling the effect of brain growth on cranial bones using finite-element analysis and geometric morphometrics.Surgical and radiologic anatomy : SRA · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Humans show a unique pattern of brain growth that differentiates us from all other primates. In this study, we use virtual endocasts to provide a detailed description of shape changes during human postnatal ontogeny with geometric morphometric methods. Using CT scans of 108 dried human crania ranging in age from newborns to adults and several hundred landmarks and semi-landmarks, we find that the endocranial ontogenetic trajectory is curvilinear with two bends, separating three distinct phases of shape change. We test to what extent endocranial shape change is driven by size increase and whether the curved ontogenetic trajectory can be explained by a simple model of modular development of the endocranial base and the endocranial vault. The hypothesis that endocranial shape change is driven exclusively by brain growth is not supported; we find changes in endocranial shape after adult size has been attained and that the transition from high rates to low rates of size increase does not correspond to one of the shape trajectory bends. The ontogenetic trajectory of the endocranial vault analyzed separately is nearly linear; the trajectory of the endocranial base, in contrast, is curved. The endocranial vault therefore acts as one developmental module during human postnatal ontogeny. Our data suggest that the cranial base comprises several submodules that follow their own temporally and/or spatially disjunct growth trajectories.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.