Evidence map›Paper›PMID 19530911›Full record

Trial reportPhotomedicine and laser surgery2009

The effect of low-level laser in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial.

Béla Hegedus, László Viharos, Mihály Gervain, Márta Gálfi

4 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Photomedicine and laser surgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 83 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02328911 phase2withdrawnnot on this mapstarted 2015, after this paper: background citation

Laser Therapy Treatment of Peripheral Neuropathic Pain in Individuals With Diabetes

TypeinterventionalSponsorUniversity of MiamiRan2015 to 2015Enrolled0ConditionsDiabetic Peripheral NeuropathyArmsLaser treatment, Sham treatment
NCT03246282 early_phase1suspendednot on this mapstarted 2017, after this paper: background citation

A Polychromatic Light Emitting Diode System to Deliver Low Dose Light Directly Into a Peripheral Intravascular Catheter: A Pain Reduction Study

TypeinterventionalSponsorJohn W. Reeves, MDRan2017 to 2018Enrolled150ConditionsPainArmsUVL1000 Treatment Station, Normal Saline 0.9% Infusion Solution Bag, Peripheral Catheterization
NCT04692597 naterminatednot on this mapstarted 2021, after this paper: background citation

Low Level Laser Therapy (LLLT) for the Treatment of Hand Osteoarthritis.

TypeinterventionalSponsorDavid MossRan2021 to 2025Enrolled83ConditionsLow Level Laser Therapy, Osteoarthritis, Family Medicine, Pain ManagementArmsPhoenix Thera-Lase System, SHAM Phoenix Thera-Lase System
NCT05403931 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effectiveness of Low Level Laser Therapy on Particular Joint Points and Acupuncture Points on Knee Joints in Grade III Knee Osteoarthritis

TypeinterventionalSponsorUniversiti Teknologi MalaysiaRan2022 to 2023Enrolled50ConditionsKnee OsteoarthritisArmsLow level laser therapy
3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Béla HegedusPhysio- and Balneotherapy Center, Orosháza-Gyopáros, Hungary. arthrodent@freemail.hu
László Viharos
Mihály Gervain
Márta Gálfi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLow-level laser therapy (LLLT) is thought to have an analgesic effect as well as a biomodulatory effect on microcirculation. This study was designed to examine the pain-relieving effect of LLLT and possible microcirculatory changes measured by thermography in patients with knee osteoarthritis (KOA). MATERIALS AND

methodsPatients with mild or moderate KOA were randomized to receive either LLLT or placebo LLLT. Treatments were delivered twice a week over a period of 4 wk with a diode laser (wavelength 830 nm, continuous wave, power 50 mW) in skin contact at a dose of 6 J/point. The placebo control group was treated with an ineffective probe (power 0.5 mW) of the same appearance. Before examinations and immediately, 2 wk, and 2 mo after completing the therapy, thermography was performed (bilateral comparative thermograph by AGA infrared camera); joint flexion, circumference, and pressure sensitivity were measured; and the visual analogue scale was recorded.

resultsIn the group treated with active LLLT, a significant improvement was found in pain (before treatment [BT]: 5.75; 2 mo after treatment : 1.18); circumference (BT: 40.45; AT: 39.86); pressure sensitivity (BT: 2.33; AT: 0.77); and flexion (BT: 105.83; AT: 122.94). In the placebo group, changes in joint flexion and pain were not significant. Thermographic measurements showed at least a 0.5 degrees C increase in temperature--and thus an improvement in circulation compared to the initial values. In the placebo group, these changes did not occur.

conclusionOur results show that LLLT reduces pain in KOA and improves microcirculation in the irradiated area.

Indexed as

Low-Level Light TherapyAdultAgedDouble-Blind MethodFemaleHumansMaleMicrocirculationMiddle AgedOsteoarthritis, KneePain MeasurementThermography

Identifiers

PMID19530911
PMCPMC2957068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.