Evidence map›Paper›PMID 19530135›Full record

ReviewBirth defects research. Part C, Embryo today : reviews2009

Gene regulatory networks in embryonic stem cells and brain development.

Dhimankrishna Ghosh, Xiaowei Yan, Qiang Tian

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Birth defects research. Part C, Embryo today : reviews, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. hUMSC vs. hUMSC-Exosome: Which One Is Better for Epilepsy?Pharmaceuticals (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dhimankrishna GhoshInstitute for Systems Biology, Seattle, Washington 98103, USA.
Xiaowei Yan
Qiang Tian

Funding

Quantitative Systems BiologyP50GM076547 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI BALIGA, NITIN S · 2006 to 2016
$30.6M
Nation Center- Integrative Biomedical Informatics(RMI)U54DA021519 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ATHEY, BRIAN DAVID · 2005 to 2010
$21.3M
QUANTITATIVE IMAGE ANALYSIS SPECIALIZED RESOURCE COREU54CA119347 · NCI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HEATH, JAMES R. · 2005 to 2009
$17.8M
Comprehensive Identification of bivalent promoters in Brain Tumor Stem CellsR21CA135339 · NCI · SWEDISH MEDICAL CENTER, FIRST HILL · PI FOLTZ, GREGORY D · 2009 to 2010
$392k
NCI NIH HHS R21 CA135339NCI NIH HHS R21CA135339NCI NIH HHS U54 CA119347NCI NIH HHS U54CA119347NIDA NIH HHS U54 DA021519NIDA NIH HHS U54DA021519NIGMS NIH HHS P50 GM076547NIGMS NIH HHS P50GM076547
6 · The paper itself

Abstract

Embryonic stem cells (ESCs) are endowed with the ability to generate multiple cell lineages and carry great therapeutic potentials in regenerative medicine. Future application of ESCs in human health and diseases will embark on the delineation of molecular mechanisms that define the biology of ESCs. Here, we discuss how the finite ESC components mediate the intriguing task of brain development and exhibit biomedical potentials to cure diverse neurological disorders.

Indexed as

Gene Regulatory NetworksAnimalsBrainBrain NeoplasmsCell DifferentiationEmbryonic DevelopmentEmbryonic Stem CellsGliomaHumansMiceNeurulationPluripotent Stem CellsRatsStem Cell Transplantation

Identifiers

PMID19530135
PMCPMC3205932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.