Evidence map›Paper›PMID 19529746›Full record

ReviewAIDS reviews

The challenge of HIV-1 antiretroviral resistance in Africa in the era of HAART.

Hakim Sendagire, Philippa J Easterbrook, Immaculate Nankya, Eric Arts, David Thomas, Steven J Reynolds

Abstract readReview
In one paragraph

Review in AIDS reviews. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Myocarditis.Lancet (London, England) · 2012
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hakim SendagireInfectious Diseases Institute, Kampala, Uganda. hsendagire@idi.co.ug
Philippa J Easterbrook
Immaculate Nankya
Eric Arts
David Thomas
Steven J Reynolds

Funding

Impact of HIV-1 Fitness on Disease ProgressionR01AI049170 · NIAID · UNIVERSITY OF WESTERN ONTARIO · PI ARTS, ERIC J · 2002 to 2024
$6.8M
Intramural NIH HHS Z99 AI999999Medical Research Council G0200585NIAID NIH HHS R01 AI049170NIAID NIH HHS Y99 AI999999
6 · The paper itself

Abstract

Antiretroviral therapy programs in Africa are currently providing treatment for almost two million people. The long-term success of large scale antiretroviral therapy programs in sub-Saharan Africa remains uncertain because of the limited information currently available on rates of virologic failure and selection for drug-resistant variants in the different HIV subtypes. This article provides a comprehensive review of the published literature on the prevalence of primary and secondary HIV drug resistance with different subtypes and in various settings across sub-Saharan Africa.

Indexed as

Antiretroviral Therapy, Highly ActiveDrug Resistance, ViralAnti-HIV AgentsDrug Therapy, CombinationGenotypeHIV-1HIV InfectionsHumansPhenotypeReverse Transcriptase InhibitorsAnti-HIV AgentsReverse Transcriptase Inhibitors

Identifiers

PMID19529746
PMCPMC3412282

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.