ArticleOptics express2006
Time resolved fluorescence tomography of turbid media based on lifetime contrast.
Article in Optics express, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed.
- Whole-body tomographic fluorescence lifetime imaging of PD-L1 expression.Research square · 2026Article
- Time-of-flight fluorescence depth mapping using a spatiotemporal deep learning model.Journal of biomedical optics · 2026Article
- Fluorescence Lifetime Imaging Enables In Vivo Quantification of PD-L1 Expression and Intertumoral Heterogeneity.Cancer research · 2025Article
- Article
- Reconstruction of fluorophore absorption and fluorescence lifetime using early photon mesoscopic fluorescence molecular tomography: a phantom study.Journal of biomedical optics · 2022Article
- Comparison of fluorescence lifetime and multispectral imaging for quantitative multiplexing in biological tissue.Biomedical optics express · 2022Article
- First Clinical Results of Fluorescence Lifetime-enhanced Tumor Imaging Using Receptor-targeted Fluorescent Probes.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022Article
- Monte Carlo-based data generation for efficient deep learning reconstruction of macroscopic diffuse optical tomography and topography applications.Journal of biomedical optics · 2022Article
- Propagation of time-resolved fluorescence in a diffuse medium: complex analytical derivation.Journal of the Optical Society of America. A, Optics, image science, and vision · 2020Article
- The Resolution Matrix in Tomographic Multiplexing: Optimization of Inter-Parameter Cross-Talk, Relative Quantitation, and Localization.IEEE transactions on bio-medical engineering · 2019Article
- Review of structured light in diffuse optical imaging.Journal of biomedical optics · 2018Review
- Laplace-domain diffuse optical measurement.Scientific reports · 2018Article
- Comparison of tomographic fluorescence spectral and lifetime multiplexing.Optics letters · 2016Article
- Substrate-based near-infrared imaging sensors enable fluorescence lifetime contrast via built-in dynamic fluorescence quenching elements.ACS sensors · 2016Article
- Optimal estimator for tomographic fluorescence lifetime multiplexing.Optics letters · 2016Article
- Fast single photon avalanche photodiode-based time-resolved diffuse optical tomography scanner.Biomedical optics express · 2015Article
- In vivo tomographic imaging of deep-seated cancer using fluorescence lifetime contrast.Cancer research · 2015Article
- Tomographic lifetime imaging using combined early- and late-arriving photons.Optics letters · 2014Article
- Resolution below the point spread function for diffuse optical imaging using fluorescence lifetime multiplexing.Optics letters · 2013Article
- Fluorescence lifetime detection in turbid media using spatial frequency domain filtering of time domain measurements.Optics letters · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
A general linear model for time domain (TD) fluorescence tomography is presented that allows a lifetime-based analysis of the entire temporal fluorescence response from a turbid medium. Simulations are used to show that TD fluorescence tomography is optimally performed using two complementary approaches: A direct TD analysis of a few time points near the peak of the temporal response, which provides superior resolution; and an asymptotic multi-exponential analysis based tomography of the decay portion of the temporal response, which provides accurate localization of yield distributions for various lifetime components present in the imaging medium. These results indicate the potential of TD technology for biomedical imaging with lifetime sensitive targeted probes, and provide useful guidelines for an optimal approach to fluorescence tomography with TD data.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.