Evidence map›Paper›PMID 19528287›Full record

ArticleAntimicrobial agents and chemotherapy2009

Synergistic interaction between silver nanoparticles and membrane-permeabilizing antimicrobial peptides.

Serge Ruden, Kai Hilpert, Marina Berditsch, Parvesh Wadhwani, Anne S Ulrich

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Metal Nanoparticles in Infection and Immunity.Immunological investigations · 2020
    Pooled it
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  18. Materials (Basel, Switzerland) · 2022
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Serge RudenKIT, IOC, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany.
Kai Hilpert
Marina Berditsch
Parvesh Wadhwani
Anne S Ulrich

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver nanoparticles, as well as antimicrobial peptides (AMPs), can be used to fight infectious diseases. Since AMPs are known to permeabilize bacterial membranes and might therefore help silver nanoparticles to access internal target sites, we investigated their combined activities and showed synergistic effects between polymyxin B and silver nanoparticles for gram-negative bacteria.

Indexed as

Metal NanoparticlesAcinetobacter calcoaceticusAnti-Bacterial AgentsAntimicrobial Cationic PeptidesDrug SynergismEnterobacterEscherichia coliGram-Negative BacteriaMicrobial Sensitivity TestsProteusPseudomonas fluorescensSilver CompoundsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesSilver Compounds

Identifiers

PMID19528287
PMCPMC2715642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.