Evidence map›Paper›PMID 19528276›Full record

ArticleAntimicrobial agents and chemotherapy2009

oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae.

Hong Bin Kim, Minghua Wang, Chi Hye Park, Eui-Chong Kim, George A Jacoby, David C Hooper

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 268 citations in OpenAlex.

  1. Article
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  8. Review
  9. Review
  10. No two are alike: on the role ofAntimicrobial agents and chemotherapy · 2025
    Article
  11. Article
  12. Molecular Epidemiology and In-Depth Characterization ofInternational journal of molecular sciences · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Resistance phenotype and virulence potential ofMicrobiology (Reading, England) · 2024
    Article
  20. Article

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Hong Bin KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Minghua Wang
Chi Hye Park
Eui-Chong Kim
George A Jacoby
David C Hooper
Massachusetts General Hospital · USHuashan Hospital · CNLahey Hospital and Medical Center · USSeoul National University · KR

Funding

Plasmid-mediated Quinolone ResistanceR01AI057576 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HOOPER, DAVID C · 2004 to 2018
$5.3M
PLASMID MEDIATED QUINOLONE RESISTANCER01AI043312 · NIAID · LAHEY CLINIC · PI JACOBY, GEORGE A · 1999 to 2007
$1.1M
NIAID NIH HHS R01 AI043312NIAID NIH HHS R01AI043312NIAID NIH HHS R01 AI057576NIAID NIH HHS R01AI057576
6 · The paper itself

Abstract

The genes for multidrug efflux pump OqxAB, which is active on fluoroquinolones, were found in human clinical isolates on a plasmid in Escherichia coli and on the chromosome of Klebsiella pneumoniae. IS26-like sequences flanked the plasmid-mediated oqxAB genes, suggesting that they had been mobilized as part of a composite transposon.

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDNA Transposable ElementsDrug Resistance, BacterialEnterobacteriaceaeEscherichia coliFluoroquinolonesHumansKlebsiella pneumoniaePlasmidsSequence Analysis, DNAAnti-Bacterial AgentsBacterial ProteinsDNA Transposable ElementsFluoroquinolones

Identifiers

PMID19528276
PMCPMC2715617
OpenAlexW2101862832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.