Trial reportThe American journal of psychiatry2009
Reducing suicidal ideation and depression in older primary care patients: 24-month outcomes of the PROSPECT study.
Trial report in The American journal of psychiatry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
108 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Algorithm-guided treatment for major depressive disorder versus treatment as usual: a systematic review.Frontiers in psychiatry · 2026Pooled it
- Pooled it
- Systematic review of structured care pathways in major depressive disorder and bipolar disorder.BMC psychiatry · 2023Pooled it
- The effectiveness of enhanced evidence-based care for depressive disorders: a meta-analysis of randomized controlled trials.Translational psychiatry · 2021Pooled it
- Improving Suicide Prevention Through Evidence-Based Strategies: A Systematic Review.The American journal of psychiatry · 2021Pooled it
- The Effectiveness of Patient-Centred Medical Home-Based Models of Care versus Standard Primary Care in Chronic Disease Management: A Systematic Review and Meta-Analysis of Randomised and Non-Randomised Controlled Trials.International journal of environmental research and public health · 2020Pooled it
- A systematic review of physical illness, functional disability, and suicidal behaviour among older adults.Aging & mental health · 2016Pooled it
- Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012Pooled it
- A systematic review of social factors and suicidal behavior in older adulthood.International journal of environmental research and public health · 2012Pooled it
- Pooled it
- Hospital-Based Psychosocial Case Management and Suicide Prevention in South Korea: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Treatment Adequacy and Adherence as Predictors of Depression Response in Primary Care.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2020Trial
- Lay-delivered behavioral activation for depressed senior center clients: Pilot RCT.International journal of geriatric psychiatry · 2019Trial
- Does a Depression Management Program Decrease Mortality in Older Adults with Specific Medical Conditions in Primary Care? An Exploratory Analysis.Journal of the American Geriatrics Society · 2016Trial
- Feasibility of integrating mental health screening and services into routine elder abuse practice to improve client outcomes.Journal of elder abuse & neglect · 2015Trial
- Adapting interpersonal psychotherapy for older adults at risk for suicide.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2015Trial
- Clinical effectiveness of integrating depression care management into medicare home health: the Depression CAREPATH Randomized trial.JAMA internal medicine · 2015Trial
- Self-help for binge eating disorder in primary care: a randomized controlled trial with ethnically and racially diverse obese patients.Behaviour research and therapy · 2013Trial
- Long term effect of depression care management on mortality in older adults: follow-up of cluster randomized clinical trial in primary care.BMJ (Clinical research ed.) · 2013Trial
- Personalised intervention for people with depression and severe COPD.The British journal of psychiatry : the journal of mental science · 2013Trial
48 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveThe Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT) evaluated the impact of a care management intervention on suicidal ideation and depression in older primary care patients. This is the first report of outcomes over a 2-year period.
methodStudy participants were patients 60 years of age or older (N=599) with major or minor depression selected after screening 9,072 randomly identified patients of 20 primary care practices randomly assigned to provide either the PROSPECT intervention or usual care. The intervention consisted of services of 15 trained care managers, who offered algorithm-based recommendations to physicians and helped patients with treatment adherence over 24 months.
resultsCompared with patients receiving usual care, those receiving the intervention had a higher likelihood of receiving antidepressants and/or psychotherapy (84.9%-89% versus 49%-62%) and had a 2.2 times greater decline in suicidal ideation over 24 months. Treatment response occurred earlier on average in the intervention group and increased from months 18 to 24, while no appreciable increase in treatment response occurred in the usual care group during the same period. Among patients with major depression, a greater number achieved remission in the intervention group than in the usual-care group at 4 months (26.6% versus 15.2%), 8 months (36% versus 22.5%), and 24 months (45.4% versus 31.5%). Patients with minor depression had favorable outcomes regardless of treatment assignment.
conclusionsSustained collaborative care maintains high utilization of depression treatment, reduces suicidal ideation, and improves the outcomes of major depression over 2 years.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.