ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2009
A critical analysis of the biological impacts of plasticizers on wildlife.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
131 citing papers in PubMed, 1 synthesis or guideline pooled it, 899 citations in OpenAlex.
- Filling gaps in population estimates of phthalate exposure globally: A systematic review and meta-analysis of international biomonitoring data.International journal of hygiene and environmental health · 2025Pooled it
- Behavioural, neurochemical, and neurohistological effects of bisphenol A and vanadium following chronic co-administration in mice.IBRO neuroscience reports · 2026Article
- Development of Membrane Transport-Inspired Biomimetic System to Degrade Plasticizers.Chemistry, an Asian journal · 2026Article
- Langmuir Monolayers as Effective Models of Apical Epithelial Cell Membranes: Studies on the Effects of Phthalate Incorporation.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- An Integrated Approach Combining Regulatory Tests inEnvironmental science & technology · 2026Article
- Toxicity of Commonly Used Plasticizers to the Freshwater Organisms Tilapia sparrmanii (Fish) and Caridina nilotica (Shrimp): Lethal and Sublethal Effects.Environmental toxicology · 2026Article
- Electrochemical Chlorine Shuttle from PVC Waste to Vinyl Ether Acceptors for the Synthesis of Biodegradable Polyester Precursors.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Perinatal exposure to the environmental pollutant butyl benzyl phthalate (BBP) induces sex-specific alterations in the neuro-immune-endocrine network in adult rats.Frontiers in immunology · 2026Article
- Assessment of bisphenol A analogues in water and sediment of an urban river system in Dhaka, Bangladesh: a regionally focused environmental investigation.RSC advances · 2025Article
- Assessment of Organic Pollutants Desorbed from Plastic Litter Items Stranded on Cadiz Beaches (SW Spain).Toxics · 2025Article
- Emerging Pollutants in Chinstrap Penguins and Krill from Deception Island (South Shetland Islands, Antarctica).Toxics · 2025Article
- Aggregation Behaviour as an Adaptive Reproductive Strategy in a Marine Ecosystem Engineer.Ecology and evolution · 2025Article
- Strategies for the Remediation of Micro- and Nanoplastics from Contaminated Food and Water: Advancements and Challenges.Journal of xenobiotics · 2025Review
- A UV-Protective Textile Coating Based on Recycled Poly(vinyl butyral) (PVB): A New Life for a Waste Polymer.Polymers · 2024Article
- IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Rodent reproductive behavior among males and females after exposure to endocrine-disrupting chemicals.Reproduction (Cambridge, England) · 2024Review
- Article
- Quantification and characterization of microplastics ingested by mangrove oysters across West Africa.Environmental science and pollution research international · 2024Article
- Endocrine disruption in teleosts and amphibians is mediated by anthropogenic and natural environmental factors: implications for risk assessment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- The tolerance of a keystone ecosystem engineer to extreme heat stress is hampered by microplastic leachates.Biology letters · 2024Article
- Comparative analysis of the bioaccumulation of bisphenol A in the blood serum and follicular fluid of women living in two areas with different environmental impacts.Frontiers in endocrinology · 2024Article
71 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 3 countries.
Funding
Abstract
This review provides a critical analysis of the biological effects of the most widely used plasticizers, including dibutyl phthalate, diethylhexyl phthalate, dimethyl phthalate, butyl benzyl phthalate and bisphenol A (BPA), on wildlife, with a focus on annelids (both aquatic and terrestrial), molluscs, crustaceans, insects, fish and amphibians. Moreover, the paper provides novel data on the biological effects of some of these plasticizers in invertebrates, fish and amphibians. Phthalates and BPA have been shown to affect reproduction in all studied animal groups, to impair development in crustaceans and amphibians and to induce genetic aberrations. Molluscs, crustaceans and amphibians appear to be especially sensitive to these compounds, and biological effects are observed at environmentally relevant exposures in the low ng l(-1) to microg l(-1) range. In contrast, most effects in fish (except for disturbance in spermatogenesis) occur at higher concentrations. Most plasticizers appear to act by interfering with the functioning of various hormone systems, but some phthalates have wider pathways of disruption. Effect concentrations of plasticizers in laboratory experiments coincide with measured environmental concentrations, and thus there is a very real potential for effects of these chemicals on some wildlife populations. The most striking gaps in our current knowledge on the impacts of plasticizers on wildlife are the lack of data for long-term exposures to environmentally relevant concentrations and their ecotoxicity when part of complex mixtures. Furthermore, the hazard of plasticizers has been investigated in annelids, molluscs and arthropods only, and given the sensitivity of some invertebrates, effects assessments are warranted in other invertebrate phyla.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.