ArticleOsteoarthritis and cartilage2009
The collagen fibril structure in the superficial zone of articular cartilage by microMRI.
Article in Osteoarthritis and cartilage, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Depth-wise multiparametric assessment of articular cartilage layers with single-sided NMR.NMR in biomedicine · 2025Article
- Study of the collagen tissue nanostructure by analyzing the echo decay obtained using the MRI technique.Soft matter · 2024Article
- Systematic review on the application of 3D-bioprinting technology in orthoregeneration: current achievements and open challenges.Journal of experimental orthopaedics · 2022Review
- The zonal evolution of collagen-network morphology quantified in early osteoarthritic grades of human cartilage.Osteoarthritis and cartilage open · 2020Article
- Quantitative µMRI and PLM study of rabbit humeral and femoral head cartilage at sub-10 µm resolutions.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020Article
- Magnetic resonance imaging (MRI) studies of knee joint under mechanical loading: Review.Magnetic resonance imaging · 2020Review
- Compressed sensing in quantitative determination of GAG concentration in cartilage by microscopic MRI.Magnetic resonance in medicine · 2018Article
- High-resolution Imaging of Myeloperoxidase Activity Sensors in Human Cerebrovascular Disease.Scientific reports · 2018Article
- Orientation anisotropy of quantitative MRI relaxation parameters in ordered tissue.Scientific reports · 2017Article
- Theory of MRI contrast in the annulus fibrosus of the intervertebral disc.Magma (New York, N.Y.) · 2016Article
- Experimental issues in the measurement of multi-component relaxation times in articular cartilage by microscopic MRI.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2013Article
- Quantitative zonal differentiation of articular cartilage by microscopic magnetic resonance imaging, polarized light microscopy, and Fourier-transform infrared imaging.Microscopy research and technique · 2013Article
- Differences in infrared spectroscopic data of connective tissues in transflectance and transmittance modes.Analytica chimica acta · 2013Article
- MRI of articular cartilage at microscopic resolution.Bone & joint research · 2013Article
- Anisotropic properties of bovine nasal cartilage.Microscopy research and technique · 2012Article
- Further studies on the anisotropic distribution of collagen in articular cartilage by μMRI.Magnetic resonance in medicine · 2011Article
- Depth-dependent anisotropies of amides and sugar in perpendicular and parallel sections of articular cartilage by Fourier transform infrared imaging.Microscopy research and technique · 2011Article
- Quantitative determination of morphological and territorial structures of articular cartilage from both perpendicular and parallel sections by polarized light microscopy.Connective tissue research · 2011Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
objectiveTo investigate the fibril architecture of the collagen matrix in the superficial zone (SZ) of articular cartilage non-destructively by microscopic magnetic resonance imaging (microMRI) T(2) anisotropy.
methodSix specimens of canine humeral cartilage were rotated in such a way that the normal axis of the articular surface of the cartilage specimen remained stationary and perpendicular to the static magnetic field, over a range of 180 degrees and at a step of 15 degrees. At each rotation angle, a quantitative T(2) image was constructed at 13 microm pixel resolution.
resultsA set of complex and depth-dependent patterns was found in the microMRI T(2) anisotropy along the depth of the tissue. In the SZ, the T(2) anisotropy is clearly periodic, which demonstrates that the distribution of the collagen fibrils in the SZ is not random. In the transitional zone, the periodicity of the T(2) anisotropy approximately doubles with respect to that in the SZ. In the initial part of the radial zone (RZ), the T(2) anisotropy is also periodic but inverse to that in the SZ. In the deep part of the RZ, the T(2) anisotropy becomes increasingly weaker and eventually disappears.
conclusionThere exists a certain degree of collagen anisotropy in all zones of articular cartilage. The anisotropic imaging data can be interpreted with the aid of a collagen architecture model.
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