ArticleBiophysical journal2009
Theory of raft formation by the cross-linking of saturated or unsaturated lipids in model lipid bilayers.
Article in Biophysical journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 20 citations in OpenAlex.
- The Membrane Phase Transition Gives Rise to Responsive Plasma Membrane Structure and Function.Cold Spring Harbor perspectives in biology · 2023Review
- The Secret Lives of Fluorescent Membrane Probes as Revealed by Molecular Dynamics Simulations.Molecules (Basel, Switzerland) · 2020Review
- Glycolipid Crosslinking Is Required for Cholera Toxin to Partition Into and Stabilize Ordered Domains.Biophysical journal · 2016Article
- Interleaflet Coupling, Pinning, and Leaflet Asymmetry-Major Players in Plasma Membrane Nanodomain Formation.Frontiers in cell and developmental biology · 2016Review
- Self-consistent mean-field model for palmitoyloleoylphosphatidylcholine-palmitoyl sphingomyelin-cholesterol lipid bilayers.Physical review. E, Statistical, nonlinear, and soft matter physics · 2011Article
- Lateral organization of complex lipid mixtures from multiscale modeling.The Journal of chemical physics · 2010Article
- Fast diffusion of very long chain saturated fatty acids across a bilayer membrane and their rapid extraction by cyclodextrins: implications for adrenoleukodystrophy.The Journal of biological chemistry · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We consider the effect of cross-linking a small fraction of lipids, either saturated or unsaturated, in a mixture of saturated and unsaturated lipids and cholesterol. The change in phase behavior is examined utilizing a recent phenomenological model of the ternary system, which is extended to include a fourth component representing the cross-linked lipids. These lipids are taken to be identical to monomeric ones except for their reduced entropy of mixing. We find that even a relatively small amount of cross-linked lipids, less than 5 mol %, is sufficient to significantly expand the range of compositions within which there is coexistence between liquid-ordered and liquid-disordered phases. Equivalently, the cross-linking of lipids increases the liquid-liquid miscibility transition temperature, and therefore could bring about phase separation at a temperature at which, before cross-linking, there was only a single liquid phase.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.