Evidence map›Paper›PMID 19527556›Full record

ReviewCanadian journal of psychiatry. Revue canadienne de psychiatrie2009

Mechanisms underlying the comorbidity of tobacco use in mental health and addictive disorders.

Dominique Morisano, Ingrid Bacher, Janet Audrain-McGovern, Tony P George

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Characteristics of alcoholic smokers, nonsmokers, and former smokers: personality, negative affect, alcohol involvement, and treatment participation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Dominique MorisanoCentre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario.
Ingrid Bacher
Janet Audrain-McGovern
Tony P George
University of Toronto · CACentre for Addiction and Mental Health · CAUniversity of Pennsylvania · US

Funding

A Behavioral Economic Approach to Smoking CessationR01CA096836 · NCI · UNIVERSITY OF PENNSYLVANIA · PI AUDRAIN-MCGOVERN, JANET E · 2003 to 2007
$2.2M
Selegiline for Smoking CessationR01DA015757 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2004 to 2007
$1.4M
Longitudinal Patterns and Predictors of Smoking BehaviorR01CA109250 · NCI · UNIVERSITY OF PENNSYLVANIA · PI AUDRAIN-MCGOVERN, JANET E · 2004 to 2008
$1.2M
Optimizing Treatment for Schizophrenic SmokersR01DA013672 · NIDA · YALE UNIVERSITY · PI GEORGE, TONY P · 2001 to 2004
$848k
Nicotinic Receptors and Cog Function in SchizophreniaR01DA014039 · NIDA · YALE UNIVERSITY · PI GEORGE, TONY P · 2001 to 2003
$627k
Translational Studies on Smoking in SchizophreniaK02DA016611 · NIDA · YALE UNIVERSITY · PI GEORGE, TONY P · 2004 to 2006
$307k
NCI NIH HHS R01-CA-109250NCI NIH HHS R01-CA-96836NIDA NIH HHS K02-DA-16611NIDA NIH HHS R01-DA-13672NIDA NIH HHS R01-DA-14039NIDA NIH HHS R01-DA-15757
6 · The paper itself

Abstract

We discuss potential explanations for the high prevalence of tobacco use and tobacco dependence (TD) in people with mental health and addictive (MHA) disorders. The biopsychosocial basis for this comorbidity is presented, integrating evidence from epidemiologic and clinical studies. We also review evidence that suggests a shared vulnerability related to biological, genetic, and environmental factors may be the most parsimonious mechanism to explain the association between TD and MHA disorders. Finally, we review the examples of various MHA disorders that are associated with TD, and suggest avenues for new investigation that could aid in the development of rationale and more effective treatments for tobacco and MHA disorder comorbidities.

Indexed as

BrainComorbidityCross-Sectional StudiesDiseases in TwinsGenetic Predisposition to DiseaseHumansMental DisordersNeurotransmitter AgentsNicotineReceptors, NeurotransmitterRisk FactorsSmokingSmoking CessationSubstance-Related DisordersTreatment OutcomeTwin Studies as TopicNeurotransmitter AgentsNicotineReceptors, Neurotransmitter

Identifiers

PMID19527556
OpenAlexW84598264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.