ArticleOrganic letters2009
Enantioselective organocatalytic Hantzsch synthesis of polyhydroquinolines.
Article in Organic letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed.
- Grignard Reagent Addition to Pyridinium Salts: A Catalytic Approach to Chiral 1,4-Dihydropyridines.ACS catalysis · 2024Article
- An enantioselective four-component reaction via assembling two reaction intermediates.Nature communications · 2022Article
- Microporous hierarchically Zn-MOF as an efficient catalyst for the Hantzsch synthesis of polyhydroquinolines.Scientific reports · 2022Article
- Mo@GAA-FeRSC advances · 2021Article
- Synthesis and biological evaluation of the new ring system benzo[RSC advances · 2021Article
- Synthesis of polyhydroquinolines and propargylamines through one-pot multicomponent reactions using an acidic ionic liquid immobilized onto magnetic FeRSC advances · 2020Article
- Amine-functionalized graphene oxide nanosheets (AFGONs): an efficient bifunctional catalyst for selective formation of 1,4-dihydropyridines, acridinediones and polyhydroquinolines.Molecular diversity · 2020Article
- Intercepted-Knoevenagel condensation for the synthesis of unsymmetrical fused-tricyclic 4Tetrahedron · 2019Article
- Lanthanide and asymmetric catalyzed syntheses of sterically hindered 4-isoxazolyl-1,4-dihydropyridines and 4-isoxazolyl-quinolones.Tetrahedron letters · 2016Article
- Asymmetric synthesis of highly functionalized tetrahydropyrans via a one-pot organocatalytic Michael/Henry/ketalization sequence.Organic letters · 2014Article
- Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation.ACS chemical biology · 2012Article
- Identification of dihydropyridines that reduce cellular tau levels.Chemical communications (Cambridge, England) · 2011Article
Corrections and comments
- Correction · 2014-10-02Error in Text · Updated to Retraction ·
- Retraction · 2021-04-27Results Not Reproducible · Upgrade/Update of Prior Notice(s) ·
- Erratum issued
- Retracted
Authors and funding
2 authors.
Funding
Abstract
The four-component Hantzsch reaction provides access to pharmaceutically important dihydropyridines. To expand the utility of this method, we have developed a route under organocatalytic conditions with good yields and excellent ee's. Through catalyst screening, we found that a BINOL-phosphoric acid allowed enantioselective synthesis of six-membered heterocycles with a variety of substitution patterns.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.