Evidence map›Paper›PMID 19526516›Full record

ArticleMagnetic resonance in medicine2009

Breathhold multiecho fast spin-echo pulse sequence for accurate R2 measurement in the heart and liver.

Daniel Kim, Jens H Jensen, Ed X Wu, Sujit S Sheth, Gary M Brittenham

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Cardiac MR Fingerprinting: Overview, Technical Developments, and Applications.Journal of magnetic resonance imaging : JMRI · 2024
    Review
  3. Article
  4. Developing a medical device-grade TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  5. Article
  6. T2 mapping in myocardial disease: a comprehensive review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Review
  7. Fast TMagnetic resonance in medicine · 2020
    Article
  8. Black blood myocardial TMagnetic resonance in medicine · 2019
    Article
  9. Inter-method reproducibility of biexponential RMagnetic resonance in medicine · 2018
    Article
  10. A multi-band double-inversion radial fast spin-echo technique for T2 cardiovascular magnetic resonance mapping of the heart.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018
    Article
  11. Review
  12. Article
  13. Article
  14. T2 mapping of the heart with a double-inversion radial fast spin-echo method with indirect echo compensation.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2015
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. MR characterization of hepatic storage iron in transfusional iron overload.Journal of magnetic resonance imaging : JMRI · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel KimDepartment of Radiology, New York University School of Medicine, New York, NY 10016, USA. kimd10@nyumc.org
Jens H Jensen
Ed X Wu
Sujit S Sheth
Gary M Brittenham

Funding

Iron Chelators Predicated on DesferrithiocinR37DK049108 · NIDDK · UNIVERSITY OF FLORIDA · PI BERGERON, RAYMOND JOSEPH · 2005 to 2014
$6.0M
ORAL IRON CHELATORS PREDICATED ON DESFERRITHIOCINR01DK049108 · NIDDK · UNIVERSITY OF FLORIDA · PI BERGERON, RAYMOND JOSEPH · 1995 to 2004
$3.2M
Quantitative Myocardial Perfusion in Assessment with MRIR01HL083309 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AXEL, LEON · 2006 to 2009
$2.2M
Magnetic Resonance Measurement of Heart and Liver IronR01DK066251 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRITTENHAM, GARY M · 2003 to 2006
$1.6M
MRI Method for In Vivo Iron QuantificationR01DK069373 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JENSEN, JENS H · 2005 to 2007
$791k
NHLBI NIH HHS R01 HL083309NIDDK NIH HHS R01 DK049108NIDDK NIH HHS R01-DK049108NIDDK NIH HHS R01 DK066251NIDDK NIH HHS R01-DK066251NIDDK NIH HHS R01 DK069373NIDDK NIH HHS R01-DK069373NIDDK NIH HHS R37 DK049108NIDDK NIH HHS R37-DK049108
6 · The paper itself

Abstract

Measurement of proton transverse relaxation rates (R(2)) is a generally useful means for quantitative characterization of pathological changes in tissue with a variety of clinical applications. The most widely used R(2) measurement method is the Carr-Purcell-Meiboom-Gill (CPMG) pulse sequence but its relatively long scan time requires respiratory gating for chest or body MRI, rendering this approach impractical for comprehensive assessment within a clinically-acceptable examination time. The purpose of our study was to develop a breathhold multiecho fast spin-echo (FSE) sequence for accurate measurement of R(2) in the liver and heart. Phantom experiments and studies of subjects in vivo were performed to compare the FSE data with the corresponding even-echo CPMG data. For pooled data, the R(2) measurements were strongly correlated (Pearson correlation coefficient = 0.99) and in excellent agreement (mean difference [CPMG - FSE] = 0.10 s(-1); 95% limits of agreement were 1.98 and -1.78 s(-1)) between the two pulse sequences.

Indexed as

Algorithmsbeta-ThalassemiaEcho-Planar ImagingFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedLiverMaleMyocardiumReproducibility of ResultsRespiratory MechanicsSensitivity and SpecificitySpin LabelsYoung AdultSpin Labels

Identifiers

PMID19526516
PMCPMC2733943

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.