Enhanced interstitial flow as a contributing factor in neointima formation: (shear) stressing vascular wall cell types other than the endothelium.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed.

1. Design considerations for engineering 3D models to study vascular pathologies in vitro.Acta biomaterialia · 2021
   Review
2. The Phenotypic Responses of Vascular Smooth Muscle Cells Exposed to Mechanical Cues.Cells · 2021
   Review
3. Local fluid transfer regulation in heart extracellular matrix.Journal of physiology and biochemistry · 2016
   Article
4. Fluid Mechanics, Arterial Disease, and Gene Expression.Annual review of fluid mechanics · 2014
   Article
5. Fluid flow mechanotransduction in vascular smooth muscle cells and fibroblasts.Annals of biomedical engineering · 2011
   Review
6. Heparan sulfate proteoglycans mediate interstitial flow mechanotransduction regulating MMP-13 expression and cell motility via FAK-ERK in 3D collagen.PloS one · 2011
   Article
7. Endothelial Cell Vascular Smooth Muscle Cell Co-Culture Assay For High Throughput Screening Assays For Discovery of Anti-Angiogenesis Agents and Other Therapeutic Molecules.International journal of high throughput screening · 2010
   Article
8. Shear stress modulation of smooth muscle cell marker genes in 2-D and 3-D depends on mechanotransduction by heparan sulfate proteoglycans and ERK1/2.PloS one · 2010
   Article
9. Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanism.American journal of physiology. Heart and circulatory physiology · 2010
   Article

Corrections and comments

• Comment on
  Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3-D collagen I via upregulation of MMP-1.2009

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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