Evidence map›Paper›PMID 19524346›Full record

ArticleSocial science & medicine (1982)2009

Association of socioeconomic status with inflammation markers in black and white men and women in the Coronary Artery Risk Development in Young Adults (CARDIA) study.

Tara L Gruenewald, Sheldon Cohen, Karen A Matthews, Russell Tracy, Teresa E Seeman

Open access · greenAbstract read
In one paragraph

Article in Social science & medicine (1982), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 2 syntheses or guidelines pooled it, 189 citations in OpenAlex.

  1. Pooled it
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  15. Association between psychosocial factors and C-reactive protein across income, race, and sex.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024
    Article
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54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Tara L GruenewaldDepartment of Medicine/Geriatrics, Geffen School of Medicine at UCLA, University of California-Los Angeles, 10945 Le Conte Ave., Los Angeles, CA 90095-1687, USA. tgruenewald@mednet.ucla.edu
Sheldon Cohen
Karen A Matthews
Russell Tracy
Teresa E Seeman
University of California, Los Angeles · USCarnegie Mellon University · USUniversity of Pittsburgh · USUniversity of Vermont · US

Funding

VASCULAR CALCIUM--AN EPIDEMIOLOGIC STUDYR01HL048050 · NHLBI · UNIVERSITY OF IOWA · PI MAHONEY, LARRY T · 1992 to 2004
$3.0M
REGULATION OF LUNG SURFACTANT PROTEIN B GENE EXPRESSIONR01HL048048 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI BOGGARAM, VIJAYAKUMAR · 1998 to 2006
$1.3M
CORONARY ARTERY DISEASE RISK DEVELOPMENT IN YOUNG ADULTS-N01HC95095-268095095N01HC095095 · HC · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILLIAMS, DALE · 1989 to 2006
$376k
CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048047 · HC · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E · 1985 to 2000
$171k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048050 · HC · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 1985 to 2000
$102k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048049 · HC · NORTHWESTERN UNIVERSITY · PI LIU, KIANG JOHN · 1985 to 2000
$71k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048048 · HC · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SCHREINER, PAMELA J · 1985 to 2000
$53k
RETROVIRAL TRANSDUCTION OF CLASS I MHC GENER01HL048049 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SACHS, DAVID H · 1993 to 1997
–
REGULATION OF LUNG SURFACTANT PROTEIN B GENE EXPRESSIONR29HL048048 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI BOGGARAM, VIJAYAKUMAR · 1993 to 1997
–
NHLBI NIH HHS N01 HC048047NHLBI NIH HHS N01 HC048048NHLBI NIH HHS N01 HC048049NHLBI NIH HHS N01 HC048050NHLBI NIH HHS N01 HC095095NHLBI NIH HHS N01-HC-48047NHLBI NIH HHS N01-HC-48048NHLBI NIH HHS N01-HC-48049NHLBI NIH HHS N01-HC-48050NHLBI NIH HHS N01-HC-95095
6 · The paper itself

Abstract

Inflammatory processes are implicated in a number of diseases for which there are known socioeconomic status (SES) disparities, including heart disease and diabetes. Growing evidence also suggests SES gradients in levels of peripheral blood markers of inflammation. However, we know little about potential gender and racial/ethnic differences in associations between SES and inflammation, despite the fact that the burden of inflammation-related diseases varies by gender and race. The present study examines SES (education and income) gradients in levels of two inflammatory biomarkers, C-reactive protein (CRP) and interleukin-6 (IL-6), in a biethnic (White and Black) sample of men and women (n=3549, aged 37-55 years) in the USA from the CARDIA Study. Health status, behavioral and psychosocial variables that may underlie SES differences in inflammatory biomarker levels were also examined. Age-adjusted CRP and IL-6 levels were inversely associated with education level in each race/gender group except Black males. Income gradients were also observed in each race/gender group for IL-6 and in White females and males for CRP. In general, differences in CRP and IL-6 levels between low and high SES groups were reduced in magnitude and significance with the addition of health status, behavioral, and psychosocial variables, although the impact of the addition of model covariates varied across race/gender groups and different SES-inflammation models. Overall, findings indicate SES gradients in levels of inflammation burden in middle-aged White and Black males and females.

Indexed as

Health Status DisparitiesSocial ClassAdolescentAdultBiomarkersBlack or African AmericanCoronary Artery DiseaseC-Reactive ProteinFemaleHumansInflammationInterleukin-6MaleMultivariate AnalysisRisk AssessmentUnited StatesBiomarkersC-Reactive ProteinInterleukin-6

Identifiers

PMID19524346
PMCPMC2747365
OpenAlexW2021094789

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.