Evidence map›Paper›PMID 19523223›Full record

ArticleChinese medicine2009

Hypoglycemic herbs and their action mechanisms.

Hongxiang Hui, George Tang, Vay Liang W Go

Open access · goldAbstract read
In one paragraph

Article in Chinese medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 195 citations in OpenAlex.

  1. Pooled it
  2. The Metabolic Effects ofNutrients · 2020
    Trial
  3. Trial
  4. Review
  5. Article
  6. Multidimensional Uses of Bitter Melon (Current organic synthesis · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. The Effects ofInternational journal of molecular sciences · 2023
    Review
  11. Upregulation of Antioxidative Gene Expression byAntioxidants (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
  14. Antidiabetic effects ofJournal of traditional and complementary medicine · 2021
    Article
  15. Article
  16. Effects ofIranian journal of medical sciences · 2020
    Article
  17. Integrative medicine research · 2019
    Article
  18. African health sciences · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Hongxiang HuiDepartment of Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA. Huihongx@gmail.com
George Tang
Vay Liang W Go
Cedars-Sinai Medical Center · USUniversity of California, Los Angeles · USVA Greater Los Angeles Healthcare System · US

Funding

UCLA Center for Excellence in Pancreatic DiseasesP01AT003960 · NCCIH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GO, VAY LIANG W · 2007 to 2011
$5.6M
NCCIH NIH HHS P01 AT003960
6 · The paper itself

Abstract

Conventional drugs treat diabetes by improving insulin sensitivity, increasing insulin production and/or decreasing the amount of glucose in blood. Several herbal preparations are used to treat diabetes, but their reported hypoglycemic effects are complex or even paradoxical in some cases. This article reviews recent findings about some of the most popular hypoglycemic herbs, such as ginseng, bitter melon and Coptis chinensis. Several popular commercially available herbal preparations are also discussed, including ADHF (anti-diabetes herbal formulation), Jiangtangkeli, YGD (Yerbe Mate-Guarana-Damiana) and BN (Byakko-ka-ninjin-to). The efficacy of hypoglycemic herbs is achieved by increasing insulin secretion, enhancing glucose uptake by adipose and muscle tissues, inhibiting glucose absorption from intestine and inhibiting glucose production from heptocytes.

Identifiers

PMID19523223
PMCPMC2704217
OpenAlexW1979154307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.