ReviewMolecular plant pathology2009
Ergot: from witchcraft to biotechnology.
Review in Molecular plant pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The development and use of decision support framework for informing selection of select agent toxins with modelling studies to inform permissible toxin amounts.Frontiers in bioengineering and biotechnology · 2022Pooled it
- Molecular Mechanisms Underlying theInternational journal of molecular sciences · 2026Review
- Article
- Article
- Innovative Detection and Mitigation of Ergot Alkaloids in Cereals: Advancing Food Safety.Metabolites · 2025Review
- Computational identification of potential antifungal targets against Claviceps purpurea via MD simulation and MM/GBSA.Scientific reports · 2025Article
- A Concise and Divergent Approach to the Naturally Occurring Tetracyclic Clavine Alkaloids (+)-Lysergol, (+)-Lysergine, and (+)-Isolysergine.The Journal of organic chemistry · 2025Article
- Design, Synthesis, and In Vitro Characterization of a Tryptamine-Based Visible-Light Photoswitchable 5-HTJournal of medicinal chemistry · 2025Article
- Unveiling nonribosomal peptide synthetases from the ergot fungusActa pharmaceutica Sinica. B · 2025Article
- The Importance of Agricultural Fungi on Human and Animal Health: Case Studies from Grains.Current topics in microbiology and immunology · 2025Review
- Valorization of milling byproducts and ergot-sclerotia-contaminated rye via clostridial ABE fermentation.Biotechnology for biofuels and bioproducts · 2024Article
- A gene regulating ergot alkaloid biosynthesis inApplied and environmental microbiology · 2024Article
- Pattern of bioterrorism in ancient times: lessons to be learned from the microbial and toxicological aspects.Wiener medizinische Wochenschrift (1946) · 2024Article
- Effects of exposure to chronic ergot alkaloids on phenylephrine contractile response of maternal pedal artery, umbilical artery, and umbilical vein in pregnant ewes.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2024Article
- Advanced Fungal Biotechnologies in Accomplishing Sustainable Development Goals (SDGs): What Do We Know and What Comes Next?Journal of fungi (Basel, Switzerland) · 2024Review
- Climate Effects on Ergot and Ergot Alkaloids Occurrence in Italian Wheat.Foods (Basel, Switzerland) · 2024Article
- A Major Facilitator Superfamily Transporter Contributes to Ergot Alkaloid Accumulation but Not Secretion inApplied microbiology (Basel, Switzerland) · 2024Article
- The C-8-S-isomers of ergot alkaloids - a review of biological and analytical aspects.Mycotoxin research · 2024Review
- Investigation of Spectroscopic Peculiarities of Ergot-Infected Winter Wheat Grains.Foods (Basel, Switzerland) · 2023Article
- Two Satellite Gene Clusters Enhance Ergot Alkaloid Biosynthesis Capacity of AspergillusApplied and environmental microbiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ergot diseases of grasses, caused by members of the genus Claviceps, have had a severe impact on human history and agriculture, causing devastating epidemics. However, ergot alkaloids, the toxic components of Claviceps sclerotia, have been used intensively (and misused) as pharmaceutical drugs, and efficient biotechnological processes have been developed for their in vitro production. Molecular genetics has provided detailed insight into the genetic basis of ergot alkaloid biosynthesis and opened up perspectives for the design of new alkaloids and the improvement of production strains; it has also revealed the refined infection strategy of this biotrophic pathogen, opening up the way for better control. Nevertheless, Claviceps remains an important pathogen worldwide, and a source for potential new drugs for central nervous system diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.