Evidence map›Paper›PMID 19522761›Full record

ArticleScandinavian journal of immunology2009

On the critique by Colin Anderson of 'A reply to Dembic: on an end to the beginning of mis-understanding the immune response'.

M Cohn

Abstract readComment
In one paragraph

Article in Scandinavian journal of immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. How do regulatory T cells work?Scandinavian journal of immunology · 2009
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

M CohnConceptual Immunology Group, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. cohn@salk.edu

Funding

EVOLUTIONARY MODELS OF THE IMMUNE SYSTEMR01RR007716 · NCRR · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI COHN, MELVIN · 1991 to 2010
$4.5M
NCRR NIH HHS R01 RR007716NCRR NIH HHS RR07716
6 · The paper itself

Abstract

My proposal of a set of postulates that can be used to guide computer modeling has understandably met with significant criticism at two levels, semantic and conceptual. The major source of contention is my assumption that the sorting of the paratopic repertoire is both necessary and sufficient to explain the evolutionarily selected mechanism for the self-nonself discrimination. While 'necessary' is agreed upon, 'sufficient' is debatable as this commentary illustrates. My essay is in defense of 'sufficiency'.

Indexed as

Models, ImmunologicalAnimalsBiological EvolutionHumansImmunity

Identifiers

PMID19522761
PMCPMC2729654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.