ReviewWorld journal of gastroenterology2009
Helicobacter pylori infection and endocrine disorders: is there a link?
Review in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05789550 (HELICOBACTER PYLORI INFECTION IN TYPE 2 DIABETES MELLITUS IN ASSIUT UNIVERSITY HOSPITAL), which is not on this map. Cited by 54 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Helicobacter pylori infection in type 2 diabetes mellitus in assiut university hospital
Who cites it
54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- Is Diabetes Mellitus a Predisposing Factor for Helicobacter pylori Infections?Current diabetes reports · 2023Pooled it
- Helicobacter pylori infection as a risk factor for diabetes: a meta-analysis of case-control studies.BMC gastroenterology · 2020Pooled it
- Preventive Effect ofGut and liver · 2026Observational
- Association between Helicobacter pylori infection and thyroid dysfunction in adults visiting a tertiary care hospital in Karachi, Pakistan: a cross-sectional study.BMC endocrine disorders · 2026Article
- Review
- Serum metabolic profiling analysis of chronic gastritis and gastric cancer by untargeted metabolomics.Annals of medicine and surgery (2012) · 2025Article
- Association betweenFrontiers in endocrinology · 2025Article
- Associations between metabolic-inflammatory biomarkers andFrontiers in nutrition · 2025Article
- Correlation between Autoimmune Hashimoto's Thyroiditis andMiddle East journal of digestive diseases · 2024Article
- Use of bidirectional Mendelian randomization to unveil the association ofScience advances · 2024Article
- H. pylori infection and osteoporosis: a large-scale observational and mendelian randomization study.BMC infectious diseases · 2024Article
- Changes in the composition of the fecal metabolome and gut microbiota contribute to intervertebral disk degeneration in a rabbit model.Journal of orthopaedic surgery and research · 2024Article
- The influence ofFrontiers in cellular and infection microbiology · 2024Article
- Review
- Long-term Effects of the Eradication ofGut and liver · 2023Article
- Association betweenFrontiers in endocrinology · 2023Article
- Impact of Active Helicobacter pylori Infection-related Metabolic Syndrome on Systemic Arterial Hypertension.Arquivos brasileiros de cardiologia · 2022Article
- Bone Fragility in Gastrointestinal Disorders.International journal of molecular sciences · 2022Review
- Association of Helicobacter pylori infection with osteoporosis risk in a physical examination population.Archives of osteoporosis · 2022Article
- Impact ofMicroorganisms · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helicobacter pylori (H pylori) infection is a leading world-wide infectious disease as it affects more than half of the world population and causes chronic gastritis, peptic ulcer disease and gastric malignancies. The infection elicits a chronic cellular inflammatory response in the gastric mucosa. However, the effects of this local inflammation may not be confined solely to the digestive tract but may spread to involve extra-intestinal tissues and/or organs. Indeed, H pylori infection has been epidemiologically linked to extra-digestive conditions and diseases. In this context, it has been speculated that H pylori infection may be responsible for various endocrine disorders, such as autoimmune thyroid diseases, diabetes mellitus, dyslipidemia, obesity, osteoporosis and primary hyperparathyroidism. This is a review of the relationship between H pylori infection and these endocrine disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.