Evidence map›Paper›PMID 19521686›Full record

ReviewCurrent topics in microbiology and immunology2009

Tracking the dynamics of salmonella specific T cell responses.

James J Moon, Stephen J McSorley

Abstract readReview
In one paragraph

Review in Current topics in microbiology and immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Review
  3. Protective immunity enhancedFrontiers in immunology · 2022
    Article
  4. Article
  5. CCR7 Deficiency Allows Accelerated Clearance ofJournal of immunology (Baltimore, Md. : 1950) · 2017
    Article
  6. U-Omp19 fromFrontiers in immunology · 2017
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Development ofVaccines · 2014
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James J MoonDepartment of Microbiology, Center for Immunology, University of Minnesota Medical, Minneapolis, MN 55455, USA.
Stephen J McSorley

Funding

CD4 T Cell Response to SalmonellaR01AI055743 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI MCSORLEY, STEPHEN J · 2004 to 2013
$3.5M
Typhoid priority antigen identification and vaccine developmentR01AI073672 · NIAID · UNIVERSITY OF MINNESOTA · PI MCSORLEY, STEPHEN J · 2008 to 2011
$1.6M
Role of Cytokines in Naive CD4+ T cell ActivationF32AI063793 · NIAID · UNIVERSITY OF MINNESOTA · PI MOON, JAMES J · 2006 to 2007
$68k
NIAID NIH HHS F32 AI063793NIAID NIH HHS R01 AI055743NIAID NIH HHS R01 AI073672
6 · The paper itself

Abstract

Over the last decade, significant advances have been made in the methodology for studying immune responses in vivo. It is now possible to follow almost every aspect of pathogen-specific immunity using in vivo models that incorporate physiological infectious doses and natural routes of infection. This new ability to study immunity in a relevant physiological context will greatly expand our understanding of the dynamic interplay between host and pathogen. Visualizing the resolution of primary infection and the development of long-term immunological memory should also aid the development of new vaccines and therapeutics for infectious diseases. In this review, we will describe the application of in vivo visualization technology to Salmonella infection, describe our current understanding of Salmonella-specific immunity, and discuss some unanswered questions that remain in this model.

Indexed as

Disease Models, AnimalSalmonellaAnimalsHumansImmunologic MemoryLymphocyte ActivationMiceMice, Inbred BALB CMice, Inbred C57BLMice, TransgenicSalmonella Infections, AnimalSalmonella typhimuriumT-LymphocytesTyphoid Fever

Identifiers

PMID19521686
PMCPMC2732114

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.