ReviewThe Canadian journal of cardiology2009
Risk prediction in cardiovascular disease: the prognostic significance of endothelial dysfunction.
Review in The Canadian journal of cardiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Comparative effects of weight loss and incretin-based therapies on vascular endothelial function, fibrinolysis and inflammation in individuals with obesity and prediabetes: A randomized controlled trial.Diabetes, obesity & metabolism · 2023Trial
- MicroRNAs in type 2 diabetes mellitus and its cardiovascular complications: mechanistic insights and translational potential.Internal and emergency medicine · 2026Review
- Association of polycystic ovary syndrome with endothelial health, cardiovascular risk, and cellular aging.Fertility and sterility · 2025Article
- Sodium-Glucose Transporter-2 Inhibitors (SGLT2i) and Myocardial Ischemia: Another Compelling Reason to Consider These Agents Regardless of Diabetes.International journal of molecular sciences · 2025Review
- Heterogeneity of Renal Endothelial Cells, Interact with Neighboring Cells, and Endothelial Injury in Chronic Kidney Disease: Mechanisms and Therapeutic Implications.International journal of medical sciences · 2025Review
- Screening of endothelial dysfunction in rheumatoid arthritis in Black African subjects in the Physiology Department of the Faculty of Medicine of Dakar: a cross-sectional study.The Pan African medical journal · 2025Article
- Review
- Antecubital venous endothelial ETB receptor protein expression is preserved with aging in men.American journal of physiology. Heart and circulatory physiology · 2024Article
- Endothelial Dysfunction and Heart Failure with Preserved Ejection Fraction-An Updated Review of the Literature.Life (Basel, Switzerland) · 2023Review
- Functional Hypothalamic Amenorrhea and Preclinical Cardiovascular Disease.The Journal of clinical endocrinology and metabolism · 2023Article
- Cardiovascular Prognosis in Patients with Peripheral Artery Disease and Approach to Therapy.Biomedicines · 2023Review
- Cilostazol regulates the expressions of endothelin-1 and endothelial nitric oxide synthase via activation of the p38 MAPK signaling pathway in HUVECs.Biomedical reports · 2022Article
- A physiologically relevant role for NO stored in vascular smooth muscle cells: A novel theory of vascular NO signaling.Redox biology · 2022Review
- Subclinical cardiovascular disease and polycystic ovary syndrome.Fertility and sterility · 2022Review
- Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation.Experimental & molecular medicine · 2022Article
- Anti-Müllerian hormone and vascular dysfunction in women with chronic kidney disease.Physiological reports · 2022Article
- Suitability of the muscle OJornal vascular brasileiro · 2021Article
- Vildagliptin, a dipeptidyl peptidase-4 inhibitor, attenuated endothelial dysfunction through miRNAs in diabetic rats.Archives of medical science : AMS · 2021Article
- Arginine and Endothelial Function.Biomedicines · 2020Review
- The Effect of Hydro-alcoholic Extract ofInternational journal of preventive medicine · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of new and emerging biomarkers in risk prediction has become a topic of significant interest and controversy in recent times. Currently, available models for risk prediction are reasonably good yet still misclassify a not insignificant portion of the population. The sheer number of new potential risk markers is daunting, and it is difficult to assess the importance of each one over and above the traditional risk factors. Endothelial function is one potential biomarker of risk that has been extensively studied. However, while it has demonstrated some utility in risk prediction, its use in daily clinical practice is yet to be clearly defined. The present review assesses the prognostic significance of measures of endothelial function.
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