Evidence map›Paper›PMID 19520990›Full record

Trial reportStroke2009

Single limb exercise induces femoral artery remodeling and improves blood flow in the hemiparetic leg poststroke.

Sandra A Billinger, Byron J Gajewski, Lisa X Guo, Patricia M Kluding

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Stroke, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Peripheral vascular function in stroke: systematic review and meta-analysis.Journal of applied physiology (Bethesda, Md. : 1985) · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Use of Pelvic Corrective Force With Visual Feedback Improves Paretic Leg Muscle Activities and Gait Performance After Stroke.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2019
    Article
  14. Article
  15. Article
  16. Time Course of Flow-Mediated Dilation and Vascular Endothelial Growth Factor following Acute Stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2018
    Article
  17. Article
  18. Article
  19. Orthostatic Reactivity in Patients with Ischemic Stroke in the Chronic Period.Open access Macedonian journal of medical sciences · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sandra A BillingerDepartment of Physical Therapy and Rehabilitation Sciences, University of Kansas Medical Center, Kansas City, KS 66160, USA. sbillinger@kumc.edu
Byron J Gajewski
Lisa X Guo
Patricia M Kluding
University of Kansas Medical Center · US

Funding

WRITING AND WT LOSS MAINTENANCEM01RR023940 · NCRR · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BURNS, JEFFREY MURRAY · 2007 to 2009
$6.6M
NCRR NIH HHS M01 RR023940
6 · The paper itself

Abstract

background and purposeAfter stroke, individuals have decreased mobility of the hemiparetic leg, which demands less muscle oxygen consumption; thus, blood flow decreases. The purpose of this study was to determine the effect of single limb exercise (SLE) on femoral artery blood flow, diameter, and peak flow velocity in the hemiparetic leg after stroke.

methodsTwelve individuals (60.6+/-14.5 years of age; 5 male) with chronic stroke (69.1+/-82.2 months; 5 with right-sided hemiparesis) participated in the study. The intervention consisted of a SLE knee extension/flexion protocol 3 times per week for 4 weeks. Using Doppler ultrasound, bilateral femoral artery blood flow, diameter, and peak flow velocity were assessed at baseline, after 2 weeks, and after 4 weeks of SLE.

resultsUsing repeated-measures analysis of variance, femoral artery blood flow, arterial diameter, and blood flow velocity in the hemiparetic limb were significantly improved (P<0.0001) after the SLE. No significant changes occurred in the nontrained limb for any outcome measures.

conclusionsThese data suggest that a 4-week SLE training program that increases muscular activity in the hemiparetic limb improves femoral artery blood flow, diameter, and peak velocity. SLE may be an important training strategy in stroke rehabilitation to minimize the vascular changes that occur poststroke due to decreased activity of the hemiparetic limb.

Indexed as

ExerciseStroke RehabilitationAgedBlood Flow VelocityFemaleFemoral ArteryHumansLegMaleMiddle AgedMuscle, SkeletalOxygen ConsumptionParesisStrokeUltrasonography, Doppler

Identifiers

PMID19520990
PMCPMC2733919
OpenAlexW2078795245

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.