Evidence map›Paper›PMID 19520789›Full record

ArticleBiostatistics (Oxford, England)2009

Variable selection and dependency networks for genomewide data.

Adrian Dobra

Abstract read
In one paragraph

Article in Biostatistics (Oxford, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Markov Neighborhood Regression for High-Dimensional Inference.Journal of the American Statistical Association · 2020
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Construction of regulatory networks using expression time-series data of a genotyped population.Proceedings of the National Academy of Sciences of the United States of America · 2011
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Adrian DobraDepartment of Statistics and Department of Biobehavioral Nursing and Health Systems, University of Washington Seattle, WA 98195, USA. adobra@u.washington.edu

Funding

Cross-species analysis of myocardial susceptibility to perioperative stressR01HL092071 · NHLBI · DUKE UNIVERSITY · PI PODGOREANU, MIHAI V. · 2007 to 2010
$1.9M
NHLBI NIH HHS R01 HL092071
6 · The paper itself

Abstract

We describe a new stochastic search algorithm for linear regression models called the bounded mode stochastic search (BMSS). We make use of BMSS to perform variable selection and classification as well as to construct sparse dependency networks. Furthermore, we show how to determine genetic networks from genomewide data that involve any combination of continuous and discrete variables. We illustrate our methodology with several real-world data sets.

Indexed as

AlgorithmsBiostatisticsBreast NeoplasmsFemaleGene ExpressionGene Regulatory NetworksGenome-Wide Association StudyHumansLinear ModelsLymphatic MetastasisReceptors, EstrogenStochastic ProcessesReceptors, Estrogen

Identifiers

PMID19520789
PMCPMC2742495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.