Evidence map›Paper›PMID 19520165›Full record

ReviewNeurobiology of disease2010

Recovery of function in humans: cortical stimulation and pharmacological treatments after stroke.

Agnes Floel, Leonardo G Cohen

Abstract readReview
In one paragraph

Review in Neurobiology of disease, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Transcranial Direct Current Stimulation and Core Stabilization Enhance Shooting Performance and Balance in Athletes: A Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Trial
  5. Diagnosing and managing post-stroke aphasia.Expert review of neurotherapeutics · 2021
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Agnes FloelDepartment of Neurology, University of Muenster, Germany. floeel@uni-muenster.de
Leonardo G Cohen

Funding

Cortical reorganization and plasticity In the Healthy BrainZIANS002978 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI COHEN, LEONARDO GREGORIO · 2009 to 2025
$38.0M
Modulating brain plasticity in rehabilitation of stroke and other brain lesionsZIANS003030 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI COHEN, LEONARDO GREGORIO · 2009 to 2025
$23.2M
Mechanisms and Modulation of Brain Plasticity in Health and DiseaseZ01NS002978 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI COHEN, LEONARDO GREGORIO · 1999 to 2008
$3.9M
Intramural NIH HHS Z01 NS002978
6 · The paper itself

Abstract

In this contribution, we first provide an overview of general principles of reorganisation in the human brain, and point out possible biomarkers of recovery. Subsequently, we expand on possibilities of adjuvant therapy in human rehabilitation using cortical stimulation and pharmacological treatments. Finally, we suggest future directions for research in this field.

Indexed as

BiomarkersCerebral CortexCholinesterase InhibitorsDopamine AgonistsElectric Stimulation TherapyHumansNerve Growth FactorsOutcome Assessment, Health CareRecovery of FunctionStrokeTranscranial Magnetic StimulationBiomarkersCholinesterase InhibitorsDopamine AgonistsNerve Growth Factors

Identifiers

PMID19520165
PMCPMC4886709

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.