Evidence map›Paper›PMID 19520017›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2009

Variations in anxiolytic and hypnotic prescribing by GPs: a cross-sectional analysis using data from the UK Quality and Outcomes Framework.

Zoi Tsimtsiou, Mark Ashworth, Roger Jones

Abstract readMulticenter Study
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Review
  7. Time Trend in Psychotropic Medication Use in Spain: A Nationwide Population-Based Study.International journal of environmental research and public health · 2016
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  9. Benzodiazepine and z-hypnotic prescribing for older people in primary care: a cross-sectional population-based study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zoi TsimtsiouDepartment of General Practice and Primary Care, King's College London School of Medicine at Guy's, King's College and St Thomas' Hospitals, London.
Mark Ashworth
Roger Jones

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWide variations in anxiolytic and hypnotic prescribing by GPs in England have been described, but are largely unexplained.

aimTo examine the relationships between the volume of anxiolytics and hypnotics prescribed by GPs and their practice characteristics, population demography, and performance indicators. DESIGN OF STUDY: Cross-sectional study.

settingAll general practices in England.

methodsA dataset was constructed for 8469 (98.8%) general practices including: standardised prescribing volume data for anxiolytics and hypnotics (average daily quantities per 1000 STAR-PUs [Specific Therapeutic group Age-sex weightings Related Prescribing Units]), practice descriptors, Index of Multiple Deprivation 2004, ethnicity data (2001 UK Census), and Quality and Outcomes Framework (QOF) data.

resultsThe standardised volume of anxiolytics and hypnotics prescribed varied eightfold between practices on the 5th and 95th centiles. A regression model was constructed which explained 20.5% of the variation. Higher prescribing practices were located in more deprived areas (standardised beta 0.31), but also in areas with a lower proportion of ethnic minorities (black or black British = -0.22; Asian or Asian British = -0.12). Higher volumes were also prescribed by practices with lower QOF scores ('Clinical Care' domain = -0.12; 'Organisational' domain = -0.08). Other significant but weaker predictors were: lower proportions of female GPs, higher recorded prevalence of serious mental illness and non-training status. The proportion of GPs trained outside UK was not a predictor.

conclusionDemographic factors were more powerful determinants of prescribing than characteristics of the practice itself. Nevertheless, the findings provide some support for the notion that high prescribing practices were less well developed, in that their QOF scores were lower and they were less likely to be training practices.

Indexed as

Family PracticeOutcome Assessment, Health CarePractice Patterns, Physicians'AgedAnti-Anxiety AgentsCross-Sectional StudiesFemaleHumansHypnotics and SedativesMaleMiddle AgedMultivariate AnalysisPrescription DrugsSocioeconomic FactorsAnti-Anxiety AgentsHypnotics and SedativesPrescription Drugs

Identifiers

PMID19520017
PMCPMC2688068

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.