ReviewJournal of biology2009
Prion variants, species barriers, generation and propagation.
Review in Journal of biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Thermodynamic and Evolutionary Coupling between the Native and Amyloid State of Globular Proteins.Cell reports · 2020Article
- Prion-like low-complexity sequences: Key regulators of protein solubility and phase behavior.The Journal of biological chemistry · 2019Review
- Protein Misfolding Cyclic Amplification Cross-Species Products of Mouse-Adapted Scrapie Strain 139A and Hamster-Adapted Scrapie Strain 263K with Brain and Muscle Tissues of Opposite Animals Generate Infectious Prions.Molecular neurobiology · 2017Article
- Structural transitions in full-length human prion protein detected by xenon as probe and spin labeling of the N-terminal domain.Scientific reports · 2016Article
- Wild yeast harbour a variety of distinct amyloid structures with strong prion-inducing capabilities.Molecular microbiology · 2014Article
- Mouse-adapted scrapie strains 139A and ME7 overcome species barrier to induce experimental scrapie in hamsters and changed their pathogenic features.Virology journal · 2012Article
- Pattern, process and the evolution of meaning: species and units of selection.Theory in biosciences = Theorie in den Biowissenschaften · 2010Article
- Strain phenomenon in protein aggregation: Interplay between sequence and conformation.Intrinsically disordered proteinsArticle
- Site-specific structural analysis of a yeast prion strain with species-specific seeding activity.PrionArticle
- Insights into prion biology: integrating a protein misfolding pathway with its cellular environment.PrionArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Prion variants faithfully propagate across species barriers, but if the barrier is too high, new variants (mutants) are selected, as shown in a recent BMC Biology report. Protein sequence alteration can prevent accurate structural templating at filament ends producing prion variants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.