Evidence map›Paper›PMID 19519924›Full record

ReviewArthritis research & therapy2009

Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases.

Sherine E Gabriel, Kaleb Michaud

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Arthritis research & therapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 345 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
345citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03106584 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Investigating the Potential for Marigot's Nutrition Supplement to Improve Symptoms and Physical Function in Those With Mild to Moderate Knee Osteoarthritis (KOA) Versus the Current Market Leader (Glucosamine Sulphate)

TypeinterventionalSponsorUniversity College DublinRan2017 to 2017Enrolled30ConditionsKnee OsteoarthritisArmsAquamin-Plus, Glucosamine sulphate
NCT05502601 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Impact of Non-surgical Periodontal Therapy in the Systemic and Clinical Conditions of Patients With Rheumatoid Arthritis: a 6-months Randomized Controlled Trial

TypeinterventionalSponsorFederal University of Rio Grande do SulRan2022 to 2025Enrolled42ConditionsArthritis, Rheumatoid, PeriodontitisArmsNon-surgical periodontal treatment
3 · Its place in the literature

Who cites it

345 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Mortality in Inflammatory Rheumatic Diseases: Lithuanian National Registry Data and Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
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  9. Trial
  10. Trial
  11. Article
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  16. Assessment of potential drug interactions in rheumatology: a comparative study of decision support software.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
    Article
  17. Emerging Therapeutics in Rheumatoid Arthritis.Current rheumatology reports · 2026
    Review
  18. Article
  19. Article
  20. Article

285 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sherine E GabrielDepartment of Health Sciences Research, Mayo Foundation, Rochester, MN 55905, USA. gabriel.sherine@mayo.edu
Kaleb Michaud

Funding

ROCHESTER EPIDEMIOLOGY PROJECTR01AR030582 · NIAMS · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A · 1986 to 2009
$5.1M
NIAMS NIH HHS R01 AR030582
6 · The paper itself

Abstract

Epidemiology is the study of the distribution and determinants of disease in human populations. Over the past decade there has been considerable progress in our understanding of the fundamental descriptive epidemiology (levels of disease frequency: incidence and prevalence, comorbidity, mortality, trends over time, geographic distributions, and clinical characteristics) of the rheumatic diseases. This progress is reviewed for the following major rheumatic diseases: rheumatoid arthritis (RA), juvenile rheumatoid arthritis, psoriatic arthritis, osteoarthritis, systemic lupus erythematosus, giant cell arteritis, polymyalgia rheumatica, gout, Sjögren's syndrome, and ankylosing spondylitis. These findings demonstrate the dynamic nature of the incidence and prevalence of these conditions--a reflection of the impact of genetic and environmental factors. The past decade has also brought new insights regarding the comorbidity associated with rheumatic diseases. Strong evidence now shows that persons with RA are at a high risk for developing several comorbid disorders, that these conditions may have atypical features and thus may be difficult to diagnose, and that persons with RA experience poorer outcomes after comorbidity compared with the general population. Taken together, these findings underscore the complexity of the rheumatic diseases and highlight the key role of epidemiological research in understanding these intriguing conditions.

Indexed as

AnimalsComorbidityHumansIncidencePrevalenceRheumatic DiseasesRisk Factors

Identifiers

PMID19519924
PMCPMC2714099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.