SynthesisDigestive diseases and sciences2010
Can endoscopic ultrasound predict early rectal cancers that can be resected endoscopically? A meta-analysis and systematic review.
Synthesis in Digestive diseases and sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Selecting patients with locally advanced rectal cancer for neoadjuvant treatment strategies.The oncologist · 2013Pooled it
- Early rectal cancer: The diagnostic performance of MRI supplemented with a rectal micro-enema and a modified staging system to identify tumors eligible for local excision.Acta radiologica open · 2024Article
- EFSUMB Recommendations for Gastrointestinal Ultrasound Part 3: Endorectal, Endoanal and Perineal Ultrasound.Ultrasound international open · 2019Review
- Endorectal ultrasound in the identification of rectal tumors for transanal endoscopic surgery: factors influencing its accuracy.Surgical endoscopy · 2018Observational
- Endoscopic ultrasound in oncology: An update of clinical applications in the gastrointestinal tract.World journal of gastrointestinal endoscopy · 2017Review
- Endoluminal high-resolution MR imaging protocol for colon walls analysis in a mouse model of colitis.Magma (New York, N.Y.) · 2016Article
- ROBIS: A new tool to assess risk of bias in systematic reviews was developed.Journal of clinical epidemiology · 2016Article
- Endoscopic Treatment of Early Cancer of the Colon.Gastroenterology & hepatology · 2015Article
- Role of endoscopic ultrasonography in the loco-regional staging of patients with rectal cancer.World journal of gastrointestinal endoscopy · 2015Review
- Endorectal ultrasonography, strain elastography and MRI differentiation of rectal adenomas and adenocarcinomas.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2015Article
- Learning curve of endorectal ultrasonography in preoperative staging of rectal carcinoma.Molecular and clinical oncology · 2014Article
- Consensus on the Prevention, Screening, Early Diagnosis and Treatment of Colorectal Tumors in China: Chinese Society of Gastroenterology, October 14-15, 2011, Shanghai, China.Gastrointestinal tumors · 2014Article
- Endoscopic ultrasound, where are we now in 2012?Clinical endoscopy · 2012Article
- Does a learning curve exist in endorectal two-dimensional ultrasound accuracy?Techniques in coloproctology · 2011Article
- How useful is rectal endosonography in the staging of rectal cancer?World journal of gastroenterology · 2010Review
- Imaging in rectal cancer with emphasis on local staging with MRI.The Indian journal of radiology & imagingArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRectal cancers that are confined to the mucosa (T0) can be resected endoscopically. This can help the patient avoid transabdominal surgery. The published data on accuracy of endoscopic ultrasound (EUS) to predict T0 stage of rectal cancers has been varied.
aimTo evaluate the accuracy of EUS in T0 staging of rectal cancers. METHOD (STUDY SELECTION CRITERIA): Only EUS studies confirmed by surgery were selected. T0 was defined as tumor confined to the mucosa. DATA COLLECTION AND EXTRACTION: Articles were searched in Medline, PubMed, and CENTRAL. STATISTICAL
methodPooling was conducted by both the fixed-effects model and random-effects model.
resultsAn initial search identified 3,360 reference articles. Of these, 339 relevant articles were selected and reviewed. Eleven studies (N = 1,791) which met the inclusion criteria were included in this analysis. Pooled sensitivity of EUS in diagnosing T0 was 97.3% (95% CI: 93.7-99.1). EUS had a pooled specificity of 96.3% (95% CI: 95.3-97.2). The positive likelihood ratio of EUS was 21.9 (95% CI: 16.3-29.7) and negative likelihood ratio was 0.08 (95% CI: 0.04-0.15). All the pooled estimates, calculated by fixed and random effect models, were similar. The P-value for Chi-squared heterogeneity for all the pooled accuracy estimates was >0.10.
conclusionsEUS has excellent sensitivity and specificity, this helps accurately diagnose T0 stage of rectal cancers. Over the past two decades, the sensitivity and specificity of EUS to diagnose T0 stage of rectal cancers has remained high. This can help physicians offer endoscopic treatment to these patients, therefore EUS should be strongly considered for staging of early rectal cancers.
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