ArticleClinical and vaccine immunology : CVI2009
Natural killer cell counts are not different between patients with post-Lyme disease syndrome and controls.
Article in Clinical and vaccine immunology : CVI, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 58 citations in OpenAlex.
- Scrutinizing Clinical Biomarkers in a Large Cohort of Patients with Lyme Disease and Other Tick-Borne Infections.Microorganisms · 2024Article
- Natural Killer Cells and Cytotoxic T Cells: Complementary Partners against Microorganisms and Cancer.Microorganisms · 2024Review
- Persistent Symptoms After Treatment of Lyme Disease.Infectious disease clinics of North America · 2022Review
- Role of NK-Like CD8Infection and immunity · 2022Article
- Immunoserological Diagnosis of Human Borrelioses: Current Knowledge and Perspectives.Frontiers in cellular and infection microbiology · 2020Review
- Current Guidelines, Common Clinical Pitfalls, and Future Directions for Laboratory Diagnosis of Lyme Disease, United States.Emerging infectious diseases · 2016Review
- Review
- Chronic Lyme disease.Infectious disease clinics of North America · 2015Review
- Laboratory diagnosis of Lyme disease: advances and challenges.Infectious disease clinics of North America · 2015Review
- New-onset panic, depression with suicidal thoughts, and somatic symptoms in a patient with a history of lyme disease.Case reports in psychiatry · 2015Article
- Functional Significance of CD57 Expression on Human NK Cells and Relevance to Disease.Frontiers in immunology · 2013Review
- Natural killer cells and natural killer T cells in Lyme arthritis.Arthritis research & therapy · 2013Article
- Antiscience and ethical concerns associated with advocacy of Lyme disease.The Lancet. Infectious diseases · 2011Article
- Lyme disease: a review.Current allergy and asthma reports · 2010Review
- Natural killer cells in chronic Lyme disease.Clinical and vaccine immunology : CVI · 2009Article
- Update on Lyme disease diagnostic approaches and protocols in Canada: Overview of existing testing strategies and limitations.Canadian family physician Medecin de famille canadienReview
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
It has been reported that patients with "chronic Lyme disease" have a decreased number of natural killer cells, as defined by the CD57 marker. We performed immunophenotyping in 9 individuals with post-Lyme disease syndrome, 12 who recovered from Lyme disease, and 9 healthy volunteers. The number of natural killer cells was not significantly different between the groups.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.