ArticleParasitology research2009
Identification of two beta-tubulin isotypes of Clonorchis sinensis.
Article in Parasitology research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 5 citations in OpenAlex.
- Identification of a Tetrahymena species infecting guppies, pathology, and expression of beta-tubulin during infection.Parasitology research · 2024Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The beta-tubulin coding sequences were investigated for the Chinese liver fluke, Clonorchis sinensis. A cDNA library of adult C. sinensis was screened with cDNA probes synthesized by polymerase chain reaction using degenerate primers, and two beta-tubulin cDNAs, CsTB1 and CsTB3, were subsequently cloned. The CsTB1 and CsTB3 cDNA were 2,082 and 1,486 bp long and encoded 445 and 444 amino acids, respectively. The two clones were identical 78% in their coding sequences and 97% in deduced sequences. Moreover, the CsTB1 had 3'-UTR 592 bp longer than that of CsTB3. The CsTB1 and CsTB3 polypeptides were highly homologous (88-99%) with those of known beta-tubulins of other helminthes with a variation at the C-terminal region. In CsTB1 and CsTB3 polypeptides, two amino acids Tyr 200 and Phe 167 were conserved. The phylogenetic analysis of selected sequences indicates that the beta-tubulins can be organized into five groups and that the two beta-tubulin isotypes of C. sinensis are contained within one group with those of other trematodes and vertebrates.
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Registered trials
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