ArticleJournal of cell science2009
Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.
Article in Journal of cell science, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Article
- CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis.The Journal of cell biology · 2020Article
- Coatopathies: Genetic Disorders of Protein Coats.Annual review of cell and developmental biology · 2019Review
- In the line-up: deleted genes associated with DiGeorge/22q11.2 deletion syndrome: are they all suspects?Journal of neurodevelopmental disorders · 2019Review
- Clathrin heavy chain 22 contributes to the control of neuropeptide degradation and secretion during neuronal development.Scientific reports · 2018Article
- CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.The Journal of biological chemistry · 2017Article
- New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision.The Journal of cell biology · 2017Article
- A novel disorder reveals clathrin heavy chain-22 is essential for human pain and touch development.Brain : a journal of neurology · 2015Article
- Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding.The Journal of cell biology · 2013Article
- Down-regulation of ANAPC13 and CLTCL1: Early Events in the Progression of Preinvasive Ductal Carcinoma of the Breast.Translational oncology · 2012Article
- Functional analysis of interaction sites on the N-terminal domain of clathrin heavy chain.Traffic (Copenhagen, Denmark) · 2012Article
- The role of clathrin in mitotic spindle organisation.Journal of cell science · 2012Review
- Aurora A kinase activity is required for localization of TACC3/ch-TOG/clathrin inter-microtubule bridges.Communicative & integrative biology · 2011Article
- Mitotic moonlighting functions for membrane trafficking proteins.Traffic (Copenhagen, Denmark) · 2011Review
- Clathrin heavy chain gene fusions expressed in human cancers: analysis of cellular functions.Traffic (Copenhagen, Denmark) · 2011Article
- Pulling it together: The mitotic function of TACC3.Bioarchitecture · 2011Article
- A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging.The EMBO journal · 2011Article
- The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.The Journal of cell biology · 2010Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Clathrin is crucial for endocytosis and plays a recently described role in mitosis. Two clathrin heavy chains (CHCs) are found in humans: the ubiquitous CHC17, and CHC22, a CHC that is enriched in skeletal muscle. Functional differences have been proposed for these clathrins despite high sequence similarity. Here, we compared each paralogue in functional assays of endocytosis and mitosis. We find that CHC17 and CHC22 are functionally equivalent. We also describe how previous work on CHC22 has involved a splice variant that is not usually expressed in cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.