Evidence map›Paper›PMID 19508940›Full record

ReviewBest practice & research. Clinical rheumatology2009

Vasculitis in children.

Despina Eleftheriou, Paul A Brogan

Open access · greenAbstract readReview
In one paragraph

Review in Best practice & research. Clinical rheumatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. The Immunogenetics of Vasculitis.Advances in experimental medicine and biology · 2022
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. [Childhood vasculitis].Zeitschrift fur Rheumatologie · 2015
    Review
  13. Henoch-Schönlein purpura nephritis in children.Nature reviews. Nephrology · 2014
    Review
  14. Article
  15. Granulomatosis with polyangiitis in childhood.Current rheumatology reports · 2012
    Review
  16. Time to focus on outcome assessment tools for childhood vasculitis.Pediatric rheumatology online journal · 2011
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Despina EleftheriouDepartment of Paediatric Rheumatology, Institute of Child Health and Great Ormond St Hospital for Children, London, UK. d.eleftheriou@ich.ucl.ac.uk
Paul A Brogan
Great Ormond Street Hospital · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary systemic vasculitides of the young are relatively rare diseases, but can have a significant morbidity and mortality. The purpose of this review is to provide an overview of the paediatric vasculitides. Vasculitides that predominantly affect children will be considered in more detail than vasculitic diseases that although are seen in children affect adults more commonly, such as the ANCA associated vasculitides. New classification criteria for childhood vasculitis have recently been proposed and are currently undergoing validation. Epidemiological clues continue to implicate infectious triggers in Kawasaki Disease and Henoch Schönlein purpura. Several genetic polymorphisms have now been described in the vasculitides that may be relevant in terms of disease predisposition or development of disease complications. Treatment regimens continue to improve, with the use of different immunosuppressive medications and newer therapeutic approaches such as biologic agents. However new challenges are looming in regards to the role of inflammation in endothelial health and the long term cardiovascular morbidity for children with primary systemic vasculitis. International multicenter collaboration is of utmost importance in order for us to further advance our understanding and improve the treatment and outcome of systemic vasculitis in the young.

Indexed as

AdolescentChildChild, PreschoolGenetic Predisposition to DiseaseHumansIgA VasculitisImmunoglobulins, IntravenousImmunosuppressive AgentsMucocutaneous Lymph Node SyndromePediatricsPolyarteritis NodosaPolymorphism, GeneticVasculitisImmunoglobulins, IntravenousImmunosuppressive Agents

Identifiers

PMID19508940
PMCPMC7106032
OpenAlexW2133451958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.