Evidence map›Paper›PMID 19508852›Full record

ReviewSeminars in cell & developmental biology2009

Regulation of Golgi function via phosphoinositide lipids.

Peter Mayinger

Abstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Signaling at the Golgi.Cold Spring Harbor perspectives in biology · 2011
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Peter MayingerDivision of Nephrology & Hypertension and Department of Cell & Developmental Biology, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA. mayinger@ohsu.edu
Oregon Health & Science University · US

Funding

Characterization of Sacl lipid phosphatasesR01GM071569 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI MAYINGER, PETER J · 2005 to 2009
$1.6M
Cell growth-dependent control of secretion by lipid signalsR01GM084088 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI MAYINGER, PETER J · 2009 to 2012
$1.2M
NIGMS NIH HHS R01 GM071569NIGMS NIH HHS R01GM071569NIGMS NIH HHS R01 GM084088
6 · The paper itself

Abstract

Phosphoinositides play important roles in Golgi traffic and structural integrity. Specific lipid kinases and phosphatases associate with the Golgi complex and regulate the multiplicity of trafficking routes from this organelle. Work in different model systems showed that the basic elements that regulate lipid signaling at the Golgi are conserved from yeast to humans. Many of the enzymes involved in Golgi phosphoinositide metabolism are essential for viability or cause severe human disease when malfunctioning. Phosphoinositide effectors at the Golgi control both non-vesicular transfer of lipids and sorting of secretory and membrane proteins. In addition, Golgi phosphoinositides were recently implicated in the metabolic and cell growth-dependent regulation of the secretory pathway.

Indexed as

AnimalsBiological TransportCell ProliferationGolgi ApparatusHumansPhosphatidylinositolsPhosphoric Monoester HydrolasesPhosphotransferasesPhosphatidylinositolsPhosphoric Monoester HydrolasesPhosphotransferases

Identifiers

PMID19508852
PMCPMC2768721
OpenAlexW2022160508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.