ArticlePigment cell & melanoma research2009
Evidence that stress to the epidermal barrier influenced the development of pigmentation in humans.
Article in Pigment cell & melanoma research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Dark Skin Evolution in Early Humans: Revisiting the Skin Cancer Hypothesis Through Migration-Related Mismatch.Molecular biology and evolution · 2026Review
- The genetic architecture of human skin pigmentation: evolution and adaptation across global populations.Frontiers in genetics · 2026Review
- The evolution of human skin pigmentation involved the interactions of genetic, environmental, and cultural variables.Pigment cell & melanoma research · 2021Review
- The Application of Skin Care Product in Melasma Treatment.Clinical, cosmetic and investigational dermatology · 2021Review
- Micropore closure time is longer following microneedle application to skin of color.Scientific reports · 2020Article
- Synergy of melanin and vitamin-D may play a fundamental role in preventing SARS-CoV-2 infections and halt COVID-19 by inactivating furin protease.Translational medicine communications · 2020Review
- By protecting against cutaneous inflammation, epidermal pigmentation provided an additional advantage for ancestral humans.Evolutionary applications · 2019Article
- Correlation of selected stress associated factors with vitamin D deficiency in Jordanian men and women.International journal of general medicine · 2019Article
- Comment on: The Vitamin D⁻Folate Hypothesis as an Evolutionary Model for Skin Pigmentation: An Update and Integration of Current Ideas,Nutrients · 2018Article
- Personalized skincare: from molecular basis to clinical and commercial applications.Clinical, cosmetic and investigational dermatology · 2018Review
- Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols.Scientific reports · 2017Article
- The colours of humanity: the evolution of pigmentation in the human lineage.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- The vitamin D hypothesis: Dead or alive?: Response to Dr. William Grant's "The UVB-vitamin D3-pigment hypothesis is alive and well-AJPA-2016-00237".American journal of physical anthropology · 2016Article
- Anti-Melanogenic Activities of Heracleum moellendorffii via ERK1/2-Mediated MITF Downregulation.International journal of molecular sciences · 2016Article
- Recent Positive Selection in Genes of the Mammalian Epidermal Differentiation Complex Locus.Frontiers in genetics · 2016Article
- Cellular Anti-Melanogenic Effects of a Euryale ferox Seed Extract Ethyl Acetate Fraction via the Lysosomal Degradation Machinery.International journal of molecular sciences · 2015Article
- Skin under the sun: when melanin pigment meets vitamin D.Endocrinology · 2015Article
- Basis for enhanced barrier function of pigmented skin.The Journal of investigative dermatology · 2014Article
- S-(-)-10,11-dihydroxyfarnesoic acid methyl ester inhibits melanin synthesis in murine melanocyte cells.International journal of molecular sciences · 2014Article
- Human pigmentation: A side effect adapted from a primitive organism's survival. Part 2: The melanocyte as mentor of the keratinocye.Indian dermatology online journal · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.