Evidence map›Paper›PMID 19508238›Full record

ArticleBiometrics2010

Saddlepoint approximations to the moments of multitype age-dependent branching processes, with applications.

O Hyrien, R Chen, M Mayer-Pröschel, M Noble

Abstract read
In one paragraph

Article in Biometrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Quantifying T lymphocyte turnover.Journal of theoretical biology · 2013
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Two-Type Reducible Age-Dependent Branching Processes With Non-Homogeneous Poisson Immigration.Comptes rendus de l'Academie Bulgare des sciences : sciences mathematiques et naturelles · 2011
    Article
  14. Article
  15. Article
  16. Article
  17. Modeling Cell Kinetics using Branching Processes with Non-Homogeneous Poisson Immigration.Comptes rendus de l'Academie Bulgare des sciences : sciences mathematiques et naturelles · 2010
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

O HyrienDepartment of Biostatistics and Computational Biology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, New York 14642, USA. Ollivier_Hyrien@urmc.rochester.edu
R Chen
M Mayer-Pröschel
M Noble

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8M
Modeling B Cell Vaccine Responses in Transplant RecipientsR01AI069351 · NIAID · UNIVERSITY OF ROCHESTER · PI HYRIEN, OLLIVIER, ZAND, MARTIN S · 2007 to 2016
$3.7M
STOCHASTIC MODELING OF MULTI TYPE CELL SYSTEMSR01NS039511 · NINDS · UNIVERSITY OF UTAH · PI HYRIEN, OLLIVIER · 2001 to 2011
$3.2M
Statistical Inference on Chemotherapy Effects from Flow Cytometry DataR01CA134839 · NCI · UNIVERSITY OF ROCHESTER · PI HYRIEN, OLLIVIER · 2008 to 2012
$1.2M
NCI NIH HHS R01 CA134839NIAID NIH HHS 1R01 AI069351NIAID NIH HHS N01 AI050020NIAID NIH HHS N01-AI-050020NIAID NIH HHS R01 AI069351NIEHS NIH HHS 2P30 ES001247NIEHS NIH HHS P30 ES001247NINDS NIH HHS 2R01 NS039511NINDS NIH HHS R01 NS039511
6 · The paper itself

Abstract

This article proposes saddlepoint approximations to the expectation and variance-covariance function of multitype age-dependent branching processes. The proposed approximations are found accurate, easy to implement, and much faster to compute than by simulating the process. Multiple applications are presented, including the analyses of clonal data on the generation of oligodendrocytes from their immediate progenitor cells, and on the proliferation of Hela cells. New estimators are also constructed to analyze clonal data. The proposed methods are finally used to approximate the distribution of the generation, which has recently found several applications in cell biology.

Indexed as

Cell LineageModels, StatisticalHeLa CellsHumansModels, BiologicalModels, TheoreticalOligodendrogliaStatistical DistributionsStem Cells

Identifiers

PMID19508238
PMCPMC2888915

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.