Evidence map›Paper›PMID 19507003›Full record

ArticleMolecular and cellular biochemistry2009

Cloning and identification of microRNAs in bovine alveolar macrophages.

Guangxian Xu, Yan Zhang, Hao Jia, Juan Li, Xiaoming Liu, John F Engelhardt, Yujiong Wang

Abstract read
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In one paragraph

Article in Molecular and cellular biochemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Guangxian XuCollege of Life Science, Ningxia University, Xixia District, Yinchuan, Ningxia, 750021, China.
Yan Zhang
Hao Jia
Juan Li
Xiaoming Liu
John F Engelhardt
Yujiong Wang
Ningxia University · CNUniversity of Iowa · US

Funding

Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Amy Leanne Ryan · 1998 to 2026
$30.5M
Biology of submucosal gland stem cells in the airwayR37DK047967 · NIDDK · UNIVERSITY OF IOWA · PI ENGELHARDT, JOHN F · 2005 to 2014
$3.8M
NIDDK NIH HHS P30 DK054759NIDDK NIH HHS R37 DK047967
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are a class of small non-coding RNAs found in both animal and plant cells. These approximately 19-26 nucleotide (nt) single-stranded RNAs play role in regulating gene/protein expression by either directly binding to mRNAs and inducing degradation of their target or by translational inhibition of protein expression. In this report, we described the cloning and identification of 22 microRNAs from bovine alveolar macrophage (AM). Eleven of the 22 miRNAs were novel and have not been previously identified in any species, while eight previously unidentified bovine miRNAs were identical to known ortholog miRNAs from human and/or rat (Bta-miR-141, Bta-miR-187, Bta-miR-191, Bta-miR-448, Bta-miR-589, Bta-miR-873, Bta-miR-463, and Bta-miR-562). These results add to the growing database of new miRNAs and suggest new biological functions for miRNAs in AMs. Specially, our data implicates miRNA regulation of antimicrobial targets in alveolar macrophages of bovine lung.

Indexed as

AnimalsCattleCloning, MolecularGene Expression ProfilingLungMacrophages, AlveolarMaleMicroRNAsMicroRNAs

Identifiers

PMID19507003
OpenAlexW2009616870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.